Sonoelastography for qualitative and quantitative evaluation of superficial soft tissue lesions: a feasibility study.
Eur Radiol
; 24(3): 566-73, 2014 Mar.
Article
em En
| MEDLINE
| ID: mdl-24272225
ABSTRACT
OBJECTIVES:
To evaluate the feasibility of qualitative and quantitative analysis using sonoelastography (SE) for differentiating between benign and malignant superficial soft-tissue lesions.METHODS:
For this prospective study, 32 patients with superficial soft-tissue lesions detected with grey-scale ultrasound and colour and/or power Doppler ultrasound were evaluated between October 2011 and December 2012. Qualitativeanalysis:
visual grading system was adopted according to colour variation (red-soft, green-medium, blue-hard). Quantitativeanalysis:
median and fraction area of each colour were computed within a region of interest. Differences between fraction areas and median values in compression and decompression phases were calculated. Reference standard histological findings.RESULTS:
Twelve out of 32 lesions (37.5%) were malignant. Intraclass correlation coefficient (ICC) was 0.989 (95% confidence interval [CI] 0.980-0.994, P < 0.01) with optimal reliability. Area under the curve was 0.823 (95% CI 0.677-0.969) and 0.958 (95% CI 0.989-1.019) for blue and blue area differences, and 0.777 (95% CI 0.615-0.939) and 0.629 (95% CI 0.426-0.833) for red and red area differences, respectively. Blue variations predicted malignancy more accurately (variation ≥0.431 100% sensitivity, 80% specificity); the blue area difference was highly accurate.CONCLUSIONS:
Preliminary results showed good correlations between SE and reference standards. SE could be useful in the evaluation of superficial soft tissue lesions. KEY POINTS ⢠Sonoelastography helps clarify ambiguous soft-tissue lesions identified using conventional ultrasound techniques. ⢠Addition of this tool increases the diagnostic accuracy of ultrasound. ⢠Sonoelastography provides both qualitative and quantitative analysis. ⢠Sonoelastography may help clinicians improve patient care.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Sarcoma
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Neoplasias de Tecidos Moles
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Doenças Musculoesqueléticas
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Ultrassonografia Doppler
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Técnicas de Imagem por Elasticidade
Tipo de estudo:
Clinical_trials
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Diagnostic_studies
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Guideline
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Observational_studies
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Prognostic_studies
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Qualitative_research
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Risk_factors_studies
Limite:
Adult
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Aged
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Humans
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Middle aged
Idioma:
En
Revista:
Eur Radiol
Assunto da revista:
RADIOLOGIA
Ano de publicação:
2014
Tipo de documento:
Article