Activation of CXCR7 limits atherosclerosis and improves hyperlipidemia by increasing cholesterol uptake in adipose tissue.

Li, Xiaofeng; Zhu, Mengyu; Penfold, Mark E; Koenen, Rory R; Thiemann, Anna; Heyll, Kathrin; Akhtar, Shamima; Koyadan, Seena; Wu, Zhuojun; Gremse, Felix; Kiessling, Fabian; van Zandvoort, Marc; Schall, Thomas J; Weber, Christian; Schober, Andreas

Li, Xiaofeng; Zhu, Mengyu; Penfold, Mark E; Koenen, Rory R; Thiemann, Anna; Heyll, Kathrin; Akhtar, Shamima; Koyadan, Seena; Wu, Zhuojun; Gremse, Felix; Kiessling, Fabian; van Zandvoort, Marc; Schall, Thomas J; Weber, Christian; Schober, Andreas.

Afiliação

Li X; Institute for Molecular Cardiovascular Research (X.L., R.R.K., A.T., K.H., S.A., Z.W., M.v.Z., C.W., A.S.), Core Facility Two-Photon Imaging, Interdisciplinary Center for Clinical Research Aachen (S.K.), and Experimental Molecular Imaging (F.G., F.K.), RWTH Aachen University, Aachen, Germany; Institute for Cardiovascular Prevention, Ludwig Maximilians University Munich, Munich, Germany (M.Z., R.R.K., K.H., C.W., A.S.); ChemoCentryx Inc, Mountain View, CA (M.E.P., T.J.S.); Cardiovascular Research

Circulation ; 129(11): 1244-53, 2014 Mar 18.

Article em En | MEDLINE | ID: mdl-24374972

Assuntos

Tecido Adiposo/metabolismo; Aterosclerose/metabolismo; Colesterol/metabolismo; Hiperlipidemias/metabolismo; Receptores CXCR/biossíntese; Animais; Aterosclerose/prevenção & controle; Hiperlipidemias/prevenção & controle; Ligantes; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout; Receptores CXCR/agonistas

Palavras-chave

atherosclerosis; coronary restenosis; hypercholesterolemia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tecido Adiposo / Colesterol / Aterosclerose / Receptores CXCR / Hiperlipidemias Limite: Animals Idioma: En Revista: Circulation Ano de publicação: 2014 Tipo de documento: Article

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