High frequency of beta thalassaemia in a small island population in Melanesia.
J Med Genet
; 24(6): 357-61, 1987 Jun.
Article
em En
| MEDLINE
| ID: mdl-2441058
ABSTRACT
A study of the causes of anaemia in the south west Pacific archipelago of Vanuatu has identified one island, Maewo, where the carrier rate for beta thalassaemia exceeds 20%, one of the highest recorded incidences in the world. Homozygous beta thalassaemia is a major cause of infant mortality and a serious drain on health resources on this island. Interactions of beta thalassaemia with various forms of alpha + thalassaemia were common in this population. Coexistent alpha + thalassaemia leads to better haemoglobinised and larger red cells than are seen in simple beta thalassaemia heterozygotes and screening for the latter can only be reliably carried out by Hb A2 estimation.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Talassemia
/
Globinas
País/Região como assunto:
Oceania
Idioma:
En
Revista:
J Med Genet
Ano de publicação:
1987
Tipo de documento:
Article