[24-hour monitoring central aortic pressure in patients with hypertensive disease and concomitant chronic obstructive pulmonary disease].

ABSTRACT

A total of 58 patients with essential hypertension were examined. 27 of them had a combination of essential hypertension and chronic obstructive pulmonary disease (COPD), 31 persons had isolated essential hypertension. The control group included 13 healthy individuals. The daily monitoring of blood pressure with a BPLab apparatus and the analysis of peripheral and central aortic pressure were performed. Comparison of groups was carried out using the Mann-Whitney test. The combination of hypertension and COPD was associated with increased daily and average daily peripheral and central aortic pressure compared with isolated essential hypertension and the control group. During daily monitoring of peripheral blood pressure the "dipper" type predominated in patients with isolated essential hypertension (41, 95%) and "non-dipper" type in those with comorbid disorders (44, 44%). The analysis of nocturnal blood pressure reduction in the aorta in patients with essential hypertension and COPD revealed the increased frequency of "non-dipper" type (55, 55%). The analysis of the central aortic pressure in patients with isolated essential hypertension showed the decreased incidence of "dipper" type (21, 87%). It is concluded that daily monitoring of the central aortic pressure permits to identify abnormal profiles with a higher frequency than the study of peripheral blood pressure.