Perfusion patterns in migraine with aura.
Cephalalgia
; 34(11): 870-6, 2014 Oct.
Article
em En
| MEDLINE
| ID: mdl-24554619
ABSTRACT
OBJECTIVES:
Migraine with aura is a common neurological disorder, and differentiation from transient ischemic attack or stroke based on clinical symptoms may be difficult.METHODS:
From an MRI report database we identified 33 patients with migraine with aura and compared these to 33 age-matched ischemic stroke patients regarding perfusion patterns on perfusion-weighted imaging (PWI)-derived maps time to peak (TTP), mean transit time (MTT), and cerebral blood flow and volume (CBF, CBV).RESULTS:
In 18/33 (54.5%) patients with migraine with aura, TTP showed areas of hypoperfusion, most of these not limited to the territory of a specific artery but affecting two or more vascular territories. In patients with migraine with aura, TTP (1.09 ± 0.05 vs. 1.47 ± 0.40, p < 0.001) and MTT ratios (1.01 ± 0.10 vs. 1.19 ± 0.21, p = 0.003) were significantly lower compared to patients with ischemic stroke. In contrast to this, CBF and CBV ratios did not differ significantly between both groups.CONCLUSIONS:
Migraine aura is usually associated with a perfusion deficit not limited to a specific vascular territory, and only a moderate increase of TTP. Thus, hypoperfusion restricted to a single vascular territory in combination with a marked increase of TTP or MTT may be regarded as atypical for migraine aura and suggestive of acute ischemic stroke.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Encéfalo
/
Interpretação de Imagem Assistida por Computador
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Circulação Cerebrovascular
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Acidente Vascular Cerebral
/
Enxaqueca com Aura
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Limite:
Adolescent
/
Adult
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Aged
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Female
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Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Cephalalgia
Ano de publicação:
2014
Tipo de documento:
Article
País de afiliação:
Alemanha