Immunization with genetically attenuated P. falciparum parasites induces long-lived antibodies that efficiently block hepatocyte invasion by sporozoites.

Finney, Olivia C; Keitany, Gladys J; Smithers, Hannah; Kaushansky, Alexis; Kappe, Stefan; Wang, Ruobing

Finney, Olivia C; Keitany, Gladys J; Smithers, Hannah; Kaushansky, Alexis; Kappe, Stefan; Wang, Ruobing.

Afiliação

Finney OC; Seattle Biomedical Research Institute, 307 Westlake Avenue North, Suite 500, Seattle, WA, 98109, USA.
Keitany GJ; Seattle Biomedical Research Institute, 307 Westlake Avenue North, Suite 500, Seattle, WA, 98109, USA.
Smithers H; Seattle Biomedical Research Institute, 307 Westlake Avenue North, Suite 500, Seattle, WA, 98109, USA.
Kaushansky A; Seattle Biomedical Research Institute, 307 Westlake Avenue North, Suite 500, Seattle, WA, 98109, USA.
Kappe S; Seattle Biomedical Research Institute, 307 Westlake Avenue North, Suite 500, Seattle, WA, 98109, USA.
Wang R; Seattle Biomedical Research Institute, 307 Westlake Avenue North, Suite 500, Seattle, WA, 98109, USA. Electronic address: ruobing.wang@seattlebiomed.org.

Vaccine ; 32(19): 2135-8, 2014 Apr 17.

Article em En | MEDLINE | ID: mdl-24582635

Assuntos

Anticorpos Antiprotozoários/sangue; Hepatócitos/parasitologia; Vacinas Antimaláricas/imunologia; Malária Falciparum/prevenção & controle; Linhagem Celular; Humanos; Imunidade Humoral; Plasmodium falciparum/genética; Esporozoítos/imunologia; Vacinas Atenuadas/imunologia

Palavras-chave

ISI; Malaria; PfGAP; Vaccines; Whole-parasite immunization

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Anticorpos Antiprotozoários / Malária Falciparum / Vacinas Antimaláricas / Hepatócitos Limite: Humans Idioma: En Revista: Vaccine Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google