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Cartilage-specific deletion of mTOR upregulates autophagy and protects mice from osteoarthritis.
Zhang, Yue; Vasheghani, Faezeh; Li, Ying-Hua; Blati, Meryem; Simeone, Kayla; Fahmi, Hassan; Lussier, Bertrand; Roughley, Peter; Lagares, David; Pelletier, Jean-Pierre; Martel-Pelletier, Johanne; Kapoor, Mohit.
Afiliação
  • Zhang Y; Osteoarthritis Research Unit, University of Montreal Research Centre (CRCHUM), Montreal, Quebec, Canada.
  • Vasheghani F; Osteoarthritis Research Unit, University of Montreal Research Centre (CRCHUM), Montreal, Quebec, Canada.
  • Li YH; Osteoarthritis Research Unit, University of Montreal Research Centre (CRCHUM), Montreal, Quebec, Canada.
  • Blati M; Osteoarthritis Research Unit, University of Montreal Research Centre (CRCHUM), Montreal, Quebec, Canada.
  • Simeone K; Osteoarthritis Research Unit, University of Montreal Research Centre (CRCHUM), Montreal, Quebec, Canada.
  • Fahmi H; Osteoarthritis Research Unit, University of Montreal Research Centre (CRCHUM), Montreal, Quebec, Canada.
  • Lussier B; Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Montreal, Montreal, Quebec, Canada.
  • Roughley P; Genetics Unit, Shriners Hospital, McGill University, Montreal, Quebec, Canada.
  • Lagares D; Pulmonary and Critical Care Unit and Center for Immunology and Inflammatory Diseases, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Massachusetts, USA.
  • Pelletier JP; Osteoarthritis Research Unit, University of Montreal Research Centre (CRCHUM), Montreal, Quebec, Canada.
  • Martel-Pelletier J; Osteoarthritis Research Unit, University of Montreal Research Centre (CRCHUM), Montreal, Quebec, Canada.
  • Kapoor M; Osteoarthritis Research Unit, University of Montreal Research Centre (CRCHUM), Montreal, Quebec, Canada Division of Genetics and Development, The Toronto Western Research Institute, Toronto Western Hospital, The University Health Network (UHN), Toronto, Ontario, Canada.
Ann Rheum Dis ; 74(7): 1432-40, 2015 Jul.
Article em En | MEDLINE | ID: mdl-24651621
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteoartrite / Autofagia / Cartilagem Articular / Regulação para Cima / Serina-Treonina Quinases TOR Tipo de estudo: Prognostic_studies Limite: Aged / Aged80 / Animals / Humans / Male / Middle aged Idioma: En Revista: Ann Rheum Dis Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Canadá
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteoartrite / Autofagia / Cartilagem Articular / Regulação para Cima / Serina-Treonina Quinases TOR Tipo de estudo: Prognostic_studies Limite: Aged / Aged80 / Animals / Humans / Male / Middle aged Idioma: En Revista: Ann Rheum Dis Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Canadá