Integrated genomic and functional analyses reveal glyoxalase I as a novel metabolic oncogene in human gastric cancer.

Hosoda, F; Arai, Y; Okada, N; Shimizu, H; Miyamoto, M; Kitagawa, N; Katai, H; Taniguchi, H; Yanagihara, K; Imoto, I; Inazawa, J; Ohki, M; Shibata, T

Hosoda, F; Arai, Y; Okada, N; Shimizu, H; Miyamoto, M; Kitagawa, N; Katai, H; Taniguchi, H; Yanagihara, K; Imoto, I; Inazawa, J; Ohki, M; Shibata, T.

Afiliação

Hosoda F; Division of Cancer Genomics, National Cancer Center Research Institute, Tokyo, Japan.
Arai Y; Division of Cancer Genomics, National Cancer Center Research Institute, Tokyo, Japan.
Okada N; Division of Cancer Genomics, National Cancer Center Research Institute, Tokyo, Japan.
Shimizu H; Division of Cancer Genomics, National Cancer Center Research Institute, Tokyo, Japan.
Miyamoto M; Division of Cancer Genomics, National Cancer Center Research Institute, Tokyo, Japan.
Kitagawa N; Division of Cancer Genomics, National Cancer Center Research Institute, Tokyo, Japan.
Katai H; Division of Gastric Surgery, National Cancer Center Hospital, Tokyo, Japan.
Taniguchi H; Division of Clinical Laboratory, National Cancer Center Hospital, Tokyo, Japan.
Yanagihara K; Division of Translational Research, Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, Chiba, Japan.
Imoto I; 1] Department of Molecular Cytogenetics, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan [2] Department of Human Genetics and Public Health, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan.
Inazawa J; Department of Molecular Cytogenetics, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan.
Ohki M; Division of Cancer Genomics, National Cancer Center Research Institute, Tokyo, Japan.
Shibata T; Division of Cancer Genomics, National Cancer Center Research Institute, Tokyo, Japan.

Oncogene ; 34(9): 1196-206, 2015 Feb 26.

Article em En | MEDLINE | ID: mdl-24662817

Assuntos

Cromossomos Humanos Par 6/genética; Genômica/métodos; Lactoilglutationa Liase/genética; Receptor ErbB-2/genética; Neoplasias Gástricas/genética; Animais; Linhagem Celular Tumoral; Hibridização Genômica Comparativa; Amplificação de Genes; Dosagem de Genes; Glutationa/análogos & derivados; Glutationa/metabolismo; Células HEK293; Humanos; Lactoilglutationa Liase/metabolismo; Camundongos; NF-kappa B/genética; Células NIH 3T3; Transdução de Sinais; Neoplasias Gástricas/metabolismo; Neoplasias Gástricas/patologia; Fator de Transcrição AP-1/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas / Cromossomos Humanos Par 6 / Receptor ErbB-2 / Genômica / Lactoilglutationa Liase Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Oncogene Assunto da revista: BIOLOGIA MOLECULAR / NEOPLASIAS Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Japão

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