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An evaluation of multiple phenotypic screening methods for Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae.
Hirsch, Elizabeth B; Chang, Kai-Tai; Zucchi, Paola C; Francoeur, Dennis N; Ledesma, Kimberly R; Tam, Vincent H; Lasco, Todd M.
Afiliação
  • Hirsch EB; Northeastern University School of Pharmacy, Boston, MA, USA. Electronic address: e.hirsch@neu.edu.
  • Chang KT; University of Houston College of Pharmacy, Houston, TX, USA.
  • Zucchi PC; Northeastern University School of Pharmacy, Boston, MA, USA.
  • Francoeur DN; Northeastern University School of Pharmacy, Boston, MA, USA.
  • Ledesma KR; University of Houston College of Pharmacy, Houston, TX, USA.
  • Tam VH; University of Houston College of Pharmacy, Houston, TX, USA; St. Luke's Episcopal Hospital, Houston, TX, USA.
  • Lasco TM; St. Luke's Episcopal Hospital, Houston, TX, USA.
J Infect Chemother ; 20(3): 224-7, 2014 Mar.
Article em En | MEDLINE | ID: mdl-24674388
Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae may display MICs to carbapenems within susceptible or intermediate ranges, prompting confirmatory testing. Four phenotypic methods to detect KPC producers were evaluated against a collection of clinical Enterobacteriaceae isolates. Meropenem-phenylboronic acid double disk synergy testing demonstrated the best performance with 100% sensitivity and specificity.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Bactérias / Beta-Lactamases / Técnicas de Tipagem Bacteriana / Resistência beta-Lactâmica / Klebsiella pneumoniae Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Humans Idioma: En Revista: J Infect Chemother Assunto da revista: MICROBIOLOGIA / TERAPIA POR MEDICAMENTOS Ano de publicação: 2014 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Bactérias / Beta-Lactamases / Técnicas de Tipagem Bacteriana / Resistência beta-Lactâmica / Klebsiella pneumoniae Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Humans Idioma: En Revista: J Infect Chemother Assunto da revista: MICROBIOLOGIA / TERAPIA POR MEDICAMENTOS Ano de publicação: 2014 Tipo de documento: Article