TP53 supports basal-like differentiation of mammary epithelial cells by preventing translocation of deltaNp63 into nucleoli.

Munne, Pauliina M; Gu, Yuexi; Tumiati, Manuela; Gao, Ping; Koopal, Sonja; Uusivirta, Sanna; Sawicki, Janet; Wei, Gong-Hong; Kuznetsov, Sergey G

Munne, Pauliina M; Gu, Yuexi; Tumiati, Manuela; Gao, Ping; Koopal, Sonja; Uusivirta, Sanna; Sawicki, Janet; Wei, Gong-Hong; Kuznetsov, Sergey G.

Afiliação

Munne PM; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, PO Box 20, FIN-00014, Helsinki, Finland.
Gu Y; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, PO Box 20, FIN-00014, Helsinki, Finland.
Tumiati M; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, PO Box 20, FIN-00014, Helsinki, Finland.
Gao P; Biocenter Oulu and Department of Medical Biochemistry and Molecular Biology, Faculty of Biochemistry and Molecular Medicine, University of Oulu, P.O. Box 5000, Oulu FIN-90014, Finland.
Koopal S; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, PO Box 20, FIN-00014, Helsinki, Finland.
Uusivirta S; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, PO Box 20, FIN-00014, Helsinki, Finland.
Sawicki J; Lankenau Institute for Medical Research, 100 Lancaster Avenue, Wynnewood, PA 19096, USA.
Wei GH; Biocenter Oulu and Department of Medical Biochemistry and Molecular Biology, Faculty of Biochemistry and Molecular Medicine, University of Oulu, P.O. Box 5000, Oulu FIN-90014, Finland.
Kuznetsov SG; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, PO Box 20, FIN-00014, Helsinki, Finland.

Sci Rep ; 4: 4663, 2014 Apr 11.

Article em En | MEDLINE | ID: mdl-24722541

Assuntos

Nucléolo Celular/metabolismo; Células Epiteliais/citologia; Fosfoproteínas/metabolismo; Transativadores/metabolismo; Proteína Supressora de Tumor p53/metabolismo; Animais; Proteína BRCA1/antagonistas & inibidores; Proteína BRCA1/genética; Proteína BRCA1/metabolismo; Diferenciação Celular; Linhagem Celular; Células Epiteliais/metabolismo; Transição Epitelial-Mesenquimal; Feminino; Humanos; Células MCF-7; Camundongos; Fosfoproteínas/antagonistas & inibidores; Fosfoproteínas/genética; Proteínas Proto-Oncogênicas c-mdm2/antagonistas & inibidores; Proteínas Proto-Oncogênicas c-mdm2/genética; Proteínas Proto-Oncogênicas c-mdm2/metabolismo; Interferência de RNA; RNA Interferente Pequeno/metabolismo; Transativadores/antagonistas & inibidores; Transativadores/genética; Proteína Supressora de Tumor p53/antagonistas & inibidores; Proteína Supressora de Tumor p53/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfoproteínas / Transativadores / Nucléolo Celular / Proteína Supressora de Tumor p53 / Células Epiteliais Limite: Animals / Female / Humans Idioma: En Revista: Sci Rep Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Finlândia

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