Renin angiotensin system modulates mTOR pathway through AT2R in HIVAN.

Rai, Partab; Lederman, Rivka; Haque, Shabirul; Rehman, Shabina; Kumar, Viki; Sataranatrajan, Kavithalakshmi; Malhotra, Ashwani; Kasinath, Balakuntalam S; Singhal, Pravin C

Rai, Partab; Lederman, Rivka; Haque, Shabirul; Rehman, Shabina; Kumar, Viki; Sataranatrajan, Kavithalakshmi; Malhotra, Ashwani; Kasinath, Balakuntalam S; Singhal, Pravin C.

Afiliação

Rai P; Renal Molecular Research Laboratory, Feinstein Institute for Medical Research, Hofstra North Shore LIJ Medical School, New York, NY, United States.
Lederman R; Renal Molecular Research Laboratory, Feinstein Institute for Medical Research, Hofstra North Shore LIJ Medical School, New York, NY, United States.
Haque S; Renal Molecular Research Laboratory, Feinstein Institute for Medical Research, Hofstra North Shore LIJ Medical School, New York, NY, United States.
Rehman S; Renal Molecular Research Laboratory, Feinstein Institute for Medical Research, Hofstra North Shore LIJ Medical School, New York, NY, United States.
Kumar V; Renal Molecular Research Laboratory, Feinstein Institute for Medical Research, Hofstra North Shore LIJ Medical School, New York, NY, United States.
Sataranatrajan K; University of Texas Health Science Center, San Antonio, TX, United States.
Malhotra A; Renal Molecular Research Laboratory, Feinstein Institute for Medical Research, Hofstra North Shore LIJ Medical School, New York, NY, United States.
Kasinath BS; University of Texas Health Science Center, San Antonio, TX, United States.
Singhal PC; Renal Molecular Research Laboratory, Feinstein Institute for Medical Research, Hofstra North Shore LIJ Medical School, New York, NY, United States. Electronic address: psinghal@nshs.edu.

Exp Mol Pathol ; 96(3): 431-7, 2014 Jun.

Article em En | MEDLINE | ID: mdl-24768585

Assuntos

Nefropatia Associada a AIDS/genética; Nefropatias/virologia; Receptor Tipo 2 de Angiotensina/metabolismo; Sistema Renina-Angiotensina/fisiologia; Serina-Treonina Quinases TOR/metabolismo; Amidas/farmacologia; Bloqueadores do Receptor Tipo 1 de Angiotensina II/metabolismo; Bloqueadores do Receptor Tipo 2 de Angiotensina II/metabolismo; Animais; Fumaratos/farmacologia; HIV; Nefropatias/veterinária; Losartan/farmacologia; Camundongos; Camundongos Transgênicos; Fosforilação; Receptor Tipo 2 de Angiotensina/genética; Proteínas Quinases S6 Ribossômicas 70-kDa/genética; Proteínas Quinases S6 Ribossômicas 70-kDa/metabolismo; Transdução de Sinais; Serina-Treonina Quinases TOR/genética

Palavras-chave

Angiotensin II type 1 receptor; Angiotensin II type II receptor; Renal proximal tubular cells; Renin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sistema Renina-Angiotensina / Nefropatia Associada a AIDS / Receptor Tipo 2 de Angiotensina / Serina-Treonina Quinases TOR / Nefropatias Limite: Animals Idioma: En Revista: Exp Mol Pathol Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos

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