Weight as predictors of clinical progression and treatment failure: results from the TREAT Asia Pediatric HIV Observational Database.
J Acquir Immune Defic Syndr
; 67(1): 71-6, 2014 Sep 01.
Article
em En
| MEDLINE
| ID: mdl-24872132
ABSTRACT
OBJECTIVE:
To evaluate the value of time-updated weight and height in predicting clinical progression, and immunological and virological failure in children receiving combination antiretroviral therapy (cART).METHODS:
We used Cox regression to analyze data of a cohort of Asian children.RESULTS:
A total of 2608 children were included; median age at cART was 5.7 years. Time-updated weight for age z score < -3 was associated with mortality (P < 0.001) independent of CD4% and < -2 was associated with immunological failure (P ≤ 0.03) independent of age at cART.CONCLUSIONS:
Weight monitoring provides useful data to inform clinical management of children on cART in resource-limited settings.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Estatura
/
Peso Corporal
/
Infecções por HIV
/
HIV-1
/
Fármacos Anti-HIV
Tipo de estudo:
Clinical_trials
/
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
País/Região como assunto:
Asia
Idioma:
En
Revista:
J Acquir Immune Defic Syndr
Assunto da revista:
SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS)
Ano de publicação:
2014
Tipo de documento:
Article