An examination of the relationship between hotspots and recombination associated with chromosome 21 nondisjunction.

Oliver, Tiffany Renee; Middlebrooks, Candace D; Tinker, Stuart W; Allen, Emily Graves; Bean, Lora J H; Begum, Ferdouse; Feingold, Eleanor; Chowdhury, Reshmi; Cheung, Vivian; Sherman, Stephanie L

Oliver, Tiffany Renee; Middlebrooks, Candace D; Tinker, Stuart W; Allen, Emily Graves; Bean, Lora J H; Begum, Ferdouse; Feingold, Eleanor; Chowdhury, Reshmi; Cheung, Vivian; Sherman, Stephanie L.

Afiliação

Oliver TR; Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia, United States of America; Department of Biology, Spelman College, Atlanta, Georgia, United States of America.
Middlebrooks CD; Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia, United States of America.
Tinker SW; Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia, United States of America.
Allen EG; Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia, United States of America.
Bean LJ; Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia, United States of America.
Begum F; Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
Feingold E; Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America; Department of Human Genetics, Graduate School of Public Health University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
Chowdhury R; Department of Human Genetics, Graduate School of Public Health University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
Cheung V; Howard Hughes Medical Institute, University of Michigan, Ann Arbor, Michigan, United States of America; Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, United States of America.
Sherman SL; Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia, United States of America.

PLoS One ; 9(6): e99560, 2014.

Article em En | MEDLINE | ID: mdl-24926858

Assuntos

Cromossomos Humanos Par 21/genética; Síndrome de Down/genética; Recombinação Genética; Feminino; Genótipo; Humanos; Masculino; Meiose; Não Disjunção Genética; Fatores de Risco

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Recombinação Genética / Cromossomos Humanos Par 21 / Síndrome de Down Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Male Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos

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