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Cellular senescence checkpoint function determines differential Notch1-dependent oncogenic and tumor-suppressor activities.
Kagawa, S; Natsuizaka, M; Whelan, K A; Facompre, N; Naganuma, S; Ohashi, S; Kinugasa, H; Egloff, A M; Basu, D; Gimotty, P A; Klein-Szanto, A J; Bass, A J; Wong, K-K; Diehl, J A; Rustgi, A K; Nakagawa, H.
Afiliação
  • Kagawa S; 1] Gastroenterology Division, Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA [2] Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA.
  • Natsuizaka M; 1] Gastroenterology Division, Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA [2] Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA [3] Department of Gastroenterology and Hepatology, Hokkaido University, Sapporo, Japan.
  • Whelan KA; 1] Gastroenterology Division, Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA [2] Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA.
  • Facompre N; 1] Departments of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania, Philadelphia, PA, USA [2] Philadelphia VA Medical Center, Philadelphia, PA, USA.
  • Naganuma S; 1] Gastroenterology Division, Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA [2] Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA [3] Department of Pathology, Kochi University Medical School, Kochi, Japan.
  • Ohashi S; 1] Gastroenterology Division, Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA [2] Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA [3] Department of Therapeutic Oncology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
  • Kinugasa H; 1] Gastroenterology Division, Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA [2] Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA [3] Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Phar
  • Egloff AM; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
  • Basu D; 1] Departments of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania, Philadelphia, PA, USA [2] Philadelphia VA Medical Center, Philadelphia, PA, USA.
  • Gimotty PA; 1] Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA [2] Division of Biostatistics, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA, USA.
  • Klein-Szanto AJ; Department of Pathology, Fox Chase Cancer Center, Philadelphia, PA, USA.
  • Bass AJ; 1] Department of Medicine, Harvard Medical School, Boston, MA, USA [2] Division of Cellular and Molecular Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Wong KK; 1] Department of Medicine, Harvard Medical School, Boston, MA, USA [2] Division of Cellular and Molecular Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Diehl JA; 1] Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA [2] Department of Cancer Biology, University of Pennsylvania, Philadelphia, PA, USA.
  • Rustgi AK; 1] Gastroenterology Division, Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA [2] Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA [3] Department of Genetics, University of Pennsylvania, Philadelphia, PA, USA.
  • Nakagawa H; 1] Gastroenterology Division, Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA [2] Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA.
Oncogene ; 34(18): 2347-59, 2015 Apr 30.
Article em En | MEDLINE | ID: mdl-24931169
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Esofágicas / Carcinoma de Células Escamosas / Transdução de Sinais / Proteína do Retinoblastoma / Receptor Notch1 Limite: Humans Idioma: En Revista: Oncogene Assunto da revista: BIOLOGIA MOLECULAR / NEOPLASIAS Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Esofágicas / Carcinoma de Células Escamosas / Transdução de Sinais / Proteína do Retinoblastoma / Receptor Notch1 Limite: Humans Idioma: En Revista: Oncogene Assunto da revista: BIOLOGIA MOLECULAR / NEOPLASIAS Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos