Executive summary of the GeSIDA/National AIDS Plan consensus document on antiretroviral therapy in adults infected by the human immunodeficiency virus (updated January 2014).
Enferm Infecc Microbiol Clin
; 32(7): 447-58, 2014.
Article
em En
| MEDLINE
| ID: mdl-24986715
ABSTRACT
In this update, antiretroviral therapy (ART) is recommended for all patients infected by type 1 human immunodeficiency virus (HIV-1). The strength and grade of the recommendation varies with clinical circumstances, number of CD4 cells, comorbid conditions and prevention of transmission of HIV. The objective of ART is to achieve an undetectable plasma viral load. Initial ART should always comprise a combination of 3 drugs, including 2 nucleoside reverse transcriptase inhibitors and a third drug from a different family (non-nucleoside reverse transcriptase inhibitor, protease inhibitor, or integrase inhibitor). This update presents the causes and criteria for switching ART in patients with undetectable plasma viral load and in cases of virological failure. An update is also provided for the specific criteria for ART in special situations (acute infection, HIV-2 infection, and pregnancy) and with comorbid conditions (tuberculosis or other opportunistic infections, kidney disease, liver disease, and cancer).
Palavras-chave
AIDS; Adverse reactions; Antiretroviral drugs; Antiretroviral treatment; Fármacos antirretrovirales; GeSIDA; Guideline; Guía, Recomendaciones; Human immunodeficiency virus infection; Infección por el virus de la inmunodeficiencia humana; Plan Nacional sobre el Sida; Reacciones adversas; Recommendations; Sida; Spanish National AIDS Plan; Tratamiento antirretroviral
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Síndrome da Imunodeficiência Adquirida
/
Antirretrovirais
Tipo de estudo:
Guideline
Limite:
Adult
/
Humans
País/Região como assunto:
Europa
Idioma:
En
Revista:
Enferm Infecc Microbiol Clin
Assunto da revista:
DOENCAS TRANSMISSIVEIS
/
MICROBIOLOGIA
Ano de publicação:
2014
Tipo de documento:
Article