Lymphocyte-derived interleukin-17A adds another brick in the wall of inflammation-induced breast carcinogenesis.
Oncoimmunology
; 3: e28273, 2014.
Article
em En
| MEDLINE
| ID: mdl-25050201
ABSTRACT
We have previously reported that a subset of breast tumors are infiltrated with IL-17A-producing tumor-associated lymphocytes and that IL-17A cytokine is principally associated with estrogen receptor negative (ER-) and triple negative, basal-like tumors. We established that IL-17A producing lymphocytes induced cancer cell proliferation, chemoresistance, and invasion, indicating that IL-17A is a potential therapeutic target for breast malignancies.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Oncoimmunology
Ano de publicação:
2014
Tipo de documento:
Article
País de afiliação:
França