Discrepancies in identification of left atrial enlargement using left atrial volume versus left atrial-to-aortic root ratio in dogs.
J Vet Intern Med
; 28(5): 1527-33, 2014.
Article
em En
| MEDLINE
| ID: mdl-25056960
ABSTRACT
BACKGROUND:
Left atrial size is prognostically important in dogs with myxomatous mitral valve disease (MMVD). HYPOTHESIS/OBJECTIVES:
To compare the level of agreement in identification of left atrial enlargement (LAE) between the left atrial-to-aortic root ratio (LA Ao) and left atrial volume using the biplane area-length method indexed to body weight (LA Vol/BW). ANIMALS Sixty dogs with MMVD and 22 normal dogs were prospectively studied with 2-dimensional echocardiography.METHODS:
The upper limit of normal for LA Vol/BW was defined as 1.1 mL/kg. LA Ao was deemed normal if ≤1.5. To define overall disease severity, each dog was assigned a mitral regurgitation severity score (MRSS) based on echocardiographic parameters that did not include left atrial size. ACVIM staging also was utilized.RESULTS:
Of 60 affected dogs, 20 were ACVIM Stage B1, 25 were Stage B2, and 15 were Stage C. LA Vol/BW identified LAE in 12 cases in which LA Ao was normal; 7 of these were Stage B1 and 5 were Stage B2. This diagnostic disagreement was significant (P = .00012). Of the 12 cases in which diagnostic discrepancies were identified, 5/5 of the B2 dogs and 3/7 B1 dogs had a moderate MRSS, whereas 4/7 B1 dogs had a mild MRSS. No diagnostic discrepancies between LA Ao and LA Vol/BW were apparent in dogs with a severe MRSS. CONCLUSIONS AND CLINICAL IMPORTANCE This study shows evidence of diagnostic disagreement between LA Ao and LA Vol/BW for assessment of LAE. LA Vol/BW may be superior to LA Ao for identification of mild LAE.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Aorta
/
Doenças do Cão
/
Átrios do Coração
/
Doenças das Valvas Cardíacas
/
Valva Mitral
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
Limite:
Animals
Idioma:
En
Revista:
J Vet Intern Med
Assunto da revista:
MEDICINA INTERNA
/
MEDICINA VETERINARIA
Ano de publicação:
2014
Tipo de documento:
Article
País de afiliação:
Vaticano