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Endothelial-cell FAK targeting sensitizes tumours to DNA-damaging therapy.
Tavora, Bernardo; Reynolds, Louise E; Batista, Silvia; Demircioglu, Fevzi; Fernandez, Isabelle; Lechertier, Tanguy; Lees, Delphine M; Wong, Ping-Pui; Alexopoulou, Annika; Elia, George; Clear, Andrew; Ledoux, Adeline; Hunter, Jill; Perkins, Neil; Gribben, John G; Hodivala-Dilke, Kairbaan M.
Afiliação
  • Tavora B; Adhesion and Angiogenesis Laboratory, Centre for Tumour Biology, Barts Cancer Institute, CR-UK Centre of Excellence, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK.
  • Reynolds LE; 1] Adhesion and Angiogenesis Laboratory, Centre for Tumour Biology, Barts Cancer Institute, CR-UK Centre of Excellence, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK [2].
  • Batista S; 1] Adhesion and Angiogenesis Laboratory, Centre for Tumour Biology, Barts Cancer Institute, CR-UK Centre of Excellence, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK [2].
  • Demircioglu F; 1] Adhesion and Angiogenesis Laboratory, Centre for Tumour Biology, Barts Cancer Institute, CR-UK Centre of Excellence, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK [2].
  • Fernandez I; 1] Adhesion and Angiogenesis Laboratory, Centre for Tumour Biology, Barts Cancer Institute, CR-UK Centre of Excellence, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK [2].
  • Lechertier T; 1] Adhesion and Angiogenesis Laboratory, Centre for Tumour Biology, Barts Cancer Institute, CR-UK Centre of Excellence, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK [2].
  • Lees DM; 1] Adhesion and Angiogenesis Laboratory, Centre for Tumour Biology, Barts Cancer Institute, CR-UK Centre of Excellence, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK [2].
  • Wong PP; 1] Adhesion and Angiogenesis Laboratory, Centre for Tumour Biology, Barts Cancer Institute, CR-UK Centre of Excellence, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK [2].
  • Alexopoulou A; Adhesion and Angiogenesis Laboratory, Centre for Tumour Biology, Barts Cancer Institute, CR-UK Centre of Excellence, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK.
  • Elia G; Barts Cancer Institute, CR-UK Centre of Excellence, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK.
  • Clear A; Centre for Haemato-Oncology, Barts Cancer Institute, CR-UK Centre of Excellence, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK.
  • Ledoux A; Institute for Cell and Molecular Biosciences (ICaMB), Medical School, Newcastle University, Catherine Cookson Building, Framlington Place, Newcastle upon Tyne NE2 4HH, UK.
  • Hunter J; Institute for Cell and Molecular Biosciences (ICaMB), Medical School, Newcastle University, Catherine Cookson Building, Framlington Place, Newcastle upon Tyne NE2 4HH, UK.
  • Perkins N; Institute for Cell and Molecular Biosciences (ICaMB), Medical School, Newcastle University, Catherine Cookson Building, Framlington Place, Newcastle upon Tyne NE2 4HH, UK.
  • Gribben JG; Centre for Haemato-Oncology, Barts Cancer Institute, CR-UK Centre of Excellence, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK.
  • Hodivala-Dilke KM; Adhesion and Angiogenesis Laboratory, Centre for Tumour Biology, Barts Cancer Institute, CR-UK Centre of Excellence, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK.
Nature ; 514(7520): 112-6, 2014 Oct 02.
Article em En | MEDLINE | ID: mdl-25079333

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dano ao DNA / Resistencia a Medicamentos Antineoplásicos / Células Endoteliais / Proteína-Tirosina Quinases de Adesão Focal Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Nature Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dano ao DNA / Resistencia a Medicamentos Antineoplásicos / Células Endoteliais / Proteína-Tirosina Quinases de Adesão Focal Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Nature Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Reino Unido