Loss of the tectorial membrane protein CEACAM16 enhances spontaneous, stimulus-frequency, and transiently evoked otoacoustic emissions.

Cheatham, Mary Ann; Goodyear, Richard J; Homma, Kazuaki; Legan, P Kevin; Korchagina, Julia; Naskar, Souvik; Siegel, Jonathan H; Dallos, Peter; Zheng, Jing; Richardson, Guy P

Cheatham, Mary Ann; Goodyear, Richard J; Homma, Kazuaki; Legan, P Kevin; Korchagina, Julia; Naskar, Souvik; Siegel, Jonathan H; Dallos, Peter; Zheng, Jing; Richardson, Guy P.

Afiliação

Cheatham MA; Roxelyn and Richard Pepper Department of Communication Sciences and Disorders, The Knowles Hearing Center, and m-cheatham@northwestern.edu g.p.richardson@sussex.ac.uk.
Goodyear RJ; Sussex Neuroscience, School of Life Sciences, University of Sussex, Falmer, Brighton, BN1 9QG, United Kingdom, and.
Homma K; Department of Otolaryngology-Head and Neck Surgery, The Knowles Hearing Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611.
Legan PK; Sussex Neuroscience, School of Life Sciences, University of Sussex, Falmer, Brighton, BN1 9QG, United Kingdom, and.
Korchagina J; Sussex Neuroscience, School of Life Sciences, University of Sussex, Falmer, Brighton, BN1 9QG, United Kingdom, and.
Naskar S; Sussex Neuroscience, School of Life Sciences, University of Sussex, Falmer, Brighton, BN1 9QG, United Kingdom, and.
Siegel JH; Roxelyn and Richard Pepper Department of Communication Sciences and Disorders, The Knowles Hearing Center, and.
Dallos P; Roxelyn and Richard Pepper Department of Communication Sciences and Disorders, The Knowles Hearing Center, and Department of Neurobiology, Northwestern University, Evanston, Illinois 60208.
Zheng J; Department of Otolaryngology-Head and Neck Surgery, The Knowles Hearing Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611.
Richardson GP; Sussex Neuroscience, School of Life Sciences, University of Sussex, Falmer, Brighton, BN1 9QG, United Kingdom, and m-cheatham@northwestern.edu g.p.richardson@sussex.ac.uk.

J Neurosci ; 34(31): 10325-38, 2014 Jul 30.

Article em En | MEDLINE | ID: mdl-25080593

Assuntos

Moléculas de Adesão Celular/deficiência; Proteínas da Matriz Extracelular/metabolismo; Órgão Espiral/citologia; Emissões Otoacústicas Espontâneas/fisiologia; Membrana Tectorial/fisiologia; Estimulação Acústica; Animais; Moléculas de Adesão Celular/genética; Potenciais Evocados Auditivos do Tronco Encefálico/genética; Regulação da Expressão Gênica/genética; Células HEK293; Humanos; Imunoprecipitação; Potenciais da Membrana/genética; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout; Microscopia Eletrônica de Transmissão; Emissões Otoacústicas Espontâneas/genética; Técnicas de Patch-Clamp; Membrana Tectorial/ultraestrutura; beta-Galactosidase/metabolismo

Palavras-chave

CEACAM16; Hensen's stripe; cochlea; mouse; otoacoustic emissions; tectorial membrane

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Órgão Espiral / Membrana Tectorial / Moléculas de Adesão Celular / Proteínas da Matriz Extracelular / Emissões Otoacústicas Espontâneas Limite: Animals / Humans Idioma: En Revista: J Neurosci Ano de publicação: 2014 Tipo de documento: Article

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