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Physiological roles of the pantothenate kinases.
Dansie, Lorraine E; Reeves, Stacy; Miller, Karen; Zano, Stephen P; Frank, Matthew; Pate, Caroline; Wang, Jina; Jackowski, Suzanne.
Afiliação
  • Dansie LE; *Department of Infectious Diseases, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105-3678, U.S.A.
  • Reeves S; *Department of Infectious Diseases, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105-3678, U.S.A.
  • Miller K; *Department of Infectious Diseases, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105-3678, U.S.A.
  • Zano SP; *Department of Infectious Diseases, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105-3678, U.S.A.
  • Frank M; *Department of Infectious Diseases, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105-3678, U.S.A.
  • Pate C; *Department of Infectious Diseases, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105-3678, U.S.A.
  • Wang J; *Department of Infectious Diseases, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105-3678, U.S.A.
  • Jackowski S; *Department of Infectious Diseases, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105-3678, U.S.A.
Biochem Soc Trans ; 42(4): 1033-6, 2014 Aug.
Article em En | MEDLINE | ID: mdl-25109998
ABSTRACT
CoA (coenzyme A) is an essential cofactor that is involved in many metabolic processes. CoA is derived from pantothenate in five biosynthetic reactions. The CoA biosynthetic pathway is regulated by PanKs (pantothenate kinases) and four active isoforms are expressed in mammals. The critical physiological functions of the PanKs are revealed by systematic deletion of the Pank genes in mice.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfotransferases (Aceptor do Grupo Álcool) Limite: Animals Idioma: En Revista: Biochem Soc Trans Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfotransferases (Aceptor do Grupo Álcool) Limite: Animals Idioma: En Revista: Biochem Soc Trans Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos