Conditional inactivation of Upstream Binding Factor reveals its epigenetic functions and the existence of a somatic nucleolar precursor body.

Hamdane, Nourdine; Stefanovsky, Victor Y; Tremblay, Michel G; Németh, Attila; Paquet, Eric; Lessard, Frédéric; Sanij, Elaine; Hannan, Ross; Moss, Tom

Hamdane, Nourdine; Stefanovsky, Victor Y; Tremblay, Michel G; Németh, Attila; Paquet, Eric; Lessard, Frédéric; Sanij, Elaine; Hannan, Ross; Moss, Tom.

Afiliação

Hamdane N; Laboratory of Growth and Development, St-Patrick Research Group in Basic Oncology, Cancer Division of the Quebec University Hospital Research Centre, Edifice St Patrick, Québec, Québec, Canada; Department of Molecular Biology, Medical Biochemistry and Pathology, Faculty of Medicine, Laval University
Stefanovsky VY; Laboratory of Growth and Development, St-Patrick Research Group in Basic Oncology, Cancer Division of the Quebec University Hospital Research Centre, Edifice St Patrick, Québec, Québec, Canada; Department of Molecular Biology, Medical Biochemistry and Pathology, Faculty of Medicine, Laval University
Tremblay MG; Laboratory of Growth and Development, St-Patrick Research Group in Basic Oncology, Cancer Division of the Quebec University Hospital Research Centre, Edifice St Patrick, Québec, Québec, Canada; Department of Molecular Biology, Medical Biochemistry and Pathology, Faculty of Medicine, Laval University
Németh A; Department of Biochemistry III, Biochemistry Center Regensburg, University of Regensburg, Regensburg, Germany.
Paquet E; Laboratory of Growth and Development, St-Patrick Research Group in Basic Oncology, Cancer Division of the Quebec University Hospital Research Centre, Edifice St Patrick, Québec, Québec, Canada.
Lessard F; Laboratory of Growth and Development, St-Patrick Research Group in Basic Oncology, Cancer Division of the Quebec University Hospital Research Centre, Edifice St Patrick, Québec, Québec, Canada; Department of Molecular Biology, Medical Biochemistry and Pathology, Faculty of Medicine, Laval University
Sanij E; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia; Research Division, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia.
Hannan R; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia; Research Division, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia.
Moss T; Laboratory of Growth and Development, St-Patrick Research Group in Basic Oncology, Cancer Division of the Quebec University Hospital Research Centre, Edifice St Patrick, Québec, Québec, Canada; Department of Molecular Biology, Medical Biochemistry and Pathology, Faculty of Medicine, Laval University

PLoS Genet ; 10(8): e1004505, 2014 Aug.

Article em En | MEDLINE | ID: mdl-25121932

Assuntos

Metilação de DNA/genética; Epigênese Genética; Proteínas Pol1 do Complexo de Iniciação de Transcrição/genética; Ribossomos/genética; Transcrição Gênica; Animais; Nucléolo Celular/genética; Cromatina/genética; Regulação da Expressão Gênica no Desenvolvimento; Proteínas HMGB/genética; Histonas/genética; Histonas/metabolismo; Camundongos; Oócitos/crescimento & desenvolvimento; Oócitos/metabolismo; Proteínas Pol1 do Complexo de Iniciação de Transcrição/antagonistas & inibidores; RNA Polimerase I/antagonistas & inibidores; RNA Polimerase I/genética; RNA Ribossômico/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ribossomos / Transcrição Gênica / Metilação de DNA / Proteínas Pol1 do Complexo de Iniciação de Transcrição / Epigênese Genética Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: PLoS Genet Assunto da revista: GENETICA Ano de publicação: 2014 Tipo de documento: Article

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