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A systematic analysis of biosynthetic gene clusters in the human microbiome reveals a common family of antibiotics.
Donia, Mohamed S; Cimermancic, Peter; Schulze, Christopher J; Wieland Brown, Laura C; Martin, John; Mitreva, Makedonka; Clardy, Jon; Linington, Roger G; Fischbach, Michael A.
Afiliação
  • Donia MS; Department of Bioengineering and Therapeutic Sciences and the California Institute for Quantitative Biosciences, University of California, San Francisco, San Francisco, CA 94158, USA.
  • Cimermancic P; Department of Bioengineering and Therapeutic Sciences and the California Institute for Quantitative Biosciences, University of California, San Francisco, San Francisco, CA 94158, USA.
  • Schulze CJ; Department of Chemistry and Biochemistry, University of California, Santa Cruz, Santa Cruz, CA 95064, USA.
  • Wieland Brown LC; Department of Chemistry, Indiana University, Bloomington, IN 47405, USA.
  • Martin J; The Genome Institute, Department of Medicine and Department of Genetics, Washington University School of Medicine, St. Louis, MO 63108, USA.
  • Mitreva M; The Genome Institute, Department of Medicine and Department of Genetics, Washington University School of Medicine, St. Louis, MO 63108, USA.
  • Clardy J; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.
  • Linington RG; Department of Chemistry and Biochemistry, University of California, Santa Cruz, Santa Cruz, CA 95064, USA.
  • Fischbach MA; Department of Bioengineering and Therapeutic Sciences and the California Institute for Quantitative Biosciences, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address: fischbach@fischbachgroup.org.
Cell ; 158(6): 1402-1414, 2014 Sep 11.
Article em En | MEDLINE | ID: mdl-25215495

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bactérias / Metagenômica / Microbiota Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Cell Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bactérias / Metagenômica / Microbiota Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Cell Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos