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LY2875358, a neutralizing and internalizing anti-MET bivalent antibody, inhibits HGF-dependent and HGF-independent MET activation and tumor growth.
Liu, Ling; Zeng, Wei; Wortinger, Mark A; Yan, S Betty; Cornwell, Paul; Peek, Victoria L; Stephens, Jennifer R; Tetreault, Jonathan W; Xia, Jinqi; Manro, Jason R; Credille, Kelly M; Ballard, Darryl W; Brown-Augsburger, Patricia; Wacheck, Volker; Chow, Chi-Kin; Huang, Lihua; Wang, Yong; Denning, Irene; Davies, Julian; Tang, Ying; Vaillancourt, Peter; Lu, Jirong.
Afiliação
  • Liu L; Biotechnology Discovery Research, Liu_Ling@lilly.com.
  • Zeng W; Biotechnology Discovery Research.
  • Wortinger MA; Biotechnology Discovery Research.
  • Yan SB; Oncology Discovery Research.
  • Cornwell P; Toxicology.
  • Peek VL; Oncology Discovery Research.
  • Stephens JR; Oncology Discovery Research.
  • Tetreault JW; Biotechnology Discovery Research.
  • Xia J; Biotechnology Discovery Research.
  • Manro JR; Discovery Statistics.
  • Credille KM; Diagnostic Experimental Pathology.
  • Ballard DW; Diagnostic Experimental Pathology.
  • Brown-Augsburger P; Drug Disposition.
  • Wacheck V; Oncology Medical.
  • Chow CK; Biotechnology Discovery Research.
  • Huang L; Bioproduct Research and Development.
  • Wang Y; Discovery Chemistry Research and Technologies. Lilly Research Laboratories, A Division of Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana.
  • Denning I; Biotechnology Discovery Research.
  • Davies J; Biotechnology Discovery Research.
  • Tang Y; Biotechnology Discovery Research.
  • Vaillancourt P; Biotechnology Discovery Research.
  • Lu J; Biotechnology Discovery Research.
Clin Cancer Res ; 20(23): 6059-70, 2014 Dec 01.
Article em En | MEDLINE | ID: mdl-25231402
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator de Crescimento de Hepatócito / Proteínas Proto-Oncogênicas c-met / Anticorpos Neutralizantes / Anticorpos Monoclonais Humanizados / Anticorpos Monoclonais / Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Clin Cancer Res Assunto da revista: NEOPLASIAS Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator de Crescimento de Hepatócito / Proteínas Proto-Oncogênicas c-met / Anticorpos Neutralizantes / Anticorpos Monoclonais Humanizados / Anticorpos Monoclonais / Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Clin Cancer Res Assunto da revista: NEOPLASIAS Ano de publicação: 2014 Tipo de documento: Article