Protein-based fluorescent metal nanoclusters for small molecular drug screening.
Chem Commun (Camb)
; 50(89): 13805-8, 2014 Nov 18.
Article
em En
| MEDLINE
| ID: mdl-25253537
ABSTRACT
A facile drug screening method based on synthesis of fluorescent gold nanoclusters inside albumin proteins loaded with small molecular drugs and comparing the relative fluorescence intensities of the resultant gold nanoclusters has been developed and successfully applied for the quantitative measurement of drug-protein binding constants.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Albumina Sérica
/
Nanoestruturas
/
Corantes Fluorescentes
/
Ouro
Tipo de estudo:
Diagnostic_studies
/
Screening_studies
Idioma:
En
Revista:
Chem Commun (Camb)
Assunto da revista:
QUIMICA
Ano de publicação:
2014
Tipo de documento:
Article