Metabolic engineering of rational screened Saccharopolyspora spinosa for the enhancement of spinosyns A and D production.

Jha, Amit Kumar; Pokhrel, Anaya Raj; Chaudhary, Amit Kumar; Park, Seong-Whan; Cho, Wan Je; Sohng, Jae Kyung

Jha, Amit Kumar; Pokhrel, Anaya Raj; Chaudhary, Amit Kumar; Park, Seong-Whan; Cho, Wan Je; Sohng, Jae Kyung.

Afiliação

Jha AK; Institute of Biomolecule Reconstruction (iBR), Department of Pharmaceutical Engineering, Sun Moon University, Asan 333-708, Korea.
Pokhrel AR; Institute of Biomolecule Reconstruction (iBR), Department of Pharmaceutical Engineering, Sun Moon University, Asan 333-708, Korea.
Chaudhary AK; Institute of Biomolecule Reconstruction (iBR), Department of Pharmaceutical Engineering, Sun Moon University, Asan 333-708, Korea.
Sohng JK; Institute of Biomolecule Reconstruction (iBR), Department of Pharmaceutical Engineering, Sun Moon University, Asan 333-708, Korea.

Mol Cells ; 37(10): 727-33, 2014 Oct 31.

Article em En | MEDLINE | ID: mdl-25256218

Assuntos

Inseticidas/metabolismo; Macrolídeos/metabolismo; Engenharia Metabólica/métodos; Saccharopolyspora/enzimologia; Animais; Combinação de Medicamentos; Humanos; Controle de Insetos/métodos; Inseticidas/química; Macrolídeos/química; Metionina Adenosiltransferase/genética; Metionina Adenosiltransferase/metabolismo; Nucleotidiltransferases/genética; Nucleotidiltransferases/metabolismo; Saccharopolyspora/genética; Saccharopolyspora/isolamento & purificação; Transgenes

Palavras-chave

metK1-sp; metabolic engineering; rmbA; rmbB

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Saccharopolyspora / Macrolídeos / Engenharia Metabólica / Inseticidas Limite: Animals / Humans Idioma: En Revista: Mol Cells Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2014 Tipo de documento: Article

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