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Mapping of transcription factor motifs in active chromatin identifies IRF5 as key regulator in classical Hodgkin lymphoma.
Kreher, Stephan; Bouhlel, M Amine; Cauchy, Pierre; Lamprecht, Björn; Li, Shuang; Grau, Michael; Hummel, Franziska; Köchert, Karl; Anagnostopoulos, Ioannis; Jöhrens, Korinna; Hummel, Michael; Hiscott, John; Wenzel, Sören-Sebastian; Lenz, Peter; Schneider, Markus; Küppers, Ralf; Scheidereit, Claus; Giefing, Maciej; Siebert, Reiner; Rajewsky, Klaus; Lenz, Georg; Cockerill, Peter N; Janz, Martin; Dörken, Bernd; Bonifer, Constanze; Mathas, Stephan.
Afiliação
  • Kreher S; Max-Delbrück-Center for Molecular Medicine, 13125 Berlin, Germany; Hematology, Oncology, and Tumor Immunology, Charité-Universitätsmedizin Berlin, 13353 Berlin, Germany;
  • Bouhlel MA; Leeds Institute of Molecular Medicine, University of Leeds, Leeds LS9 7TF, United Kingdom;
  • Cauchy P; School of Cancer Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, United Kingdom;
  • Lamprecht B; Max-Delbrück-Center for Molecular Medicine, 13125 Berlin, Germany; Hematology, Oncology, and Tumor Immunology, Charité-Universitätsmedizin Berlin, 13353 Berlin, Germany; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany;
  • Li S; Max-Delbrück-Center for Molecular Medicine, 13125 Berlin, Germany; Hematology, Oncology, and Tumor Immunology, Charité-Universitätsmedizin Berlin, 13353 Berlin, Germany;
  • Grau M; Department of Physics, Philipps University, 35052 Marburg, Germany;
  • Hummel F; Max-Delbrück-Center for Molecular Medicine, 13125 Berlin, Germany; Hematology, Oncology, and Tumor Immunology, Charité-Universitätsmedizin Berlin, 13353 Berlin, Germany;
  • Köchert K; Max-Delbrück-Center for Molecular Medicine, 13125 Berlin, Germany; Hematology, Oncology, and Tumor Immunology, Charité-Universitätsmedizin Berlin, 13353 Berlin, Germany;
  • Anagnostopoulos I; Institute of Pathology, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany;
  • Jöhrens K; Institute of Pathology, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany;
  • Hummel M; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany; Institute of Pathology, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany;
  • Hiscott J; Vaccine and Gene Therapy Institute of Florida, Port St. Lucie, FL 34987;
  • Wenzel SS; Hematology, Oncology, and Tumor Immunology, Charité-Universitätsmedizin Berlin, 13353 Berlin, Germany;
  • Lenz P; Department of Physics, Philipps University, 35052 Marburg, Germany;
  • Schneider M; Institute of Cell Biology (Cancer Research), University of Duisburg-Essen, 45122 Essen, Germany;
  • Küppers R; Institute of Cell Biology (Cancer Research), University of Duisburg-Essen, 45122 Essen, Germany;
  • Scheidereit C; Max-Delbrück-Center for Molecular Medicine, 13125 Berlin, Germany;
  • Giefing M; Institute of Human Genetics, Christian-Albrechts University Kiel and University Hospital Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany; and Institute of Human Genetics, Polish Academy of Sciences, 60-479 Poznan, Poland.
  • Siebert R; Institute of Human Genetics, Christian-Albrechts University Kiel and University Hospital Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany; and.
  • Rajewsky K; Max-Delbrück-Center for Molecular Medicine, 13125 Berlin, Germany;
  • Lenz G; Hematology, Oncology, and Tumor Immunology, Charité-Universitätsmedizin Berlin, 13353 Berlin, Germany;
  • Cockerill PN; School of Cancer Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, United Kingdom;
  • Janz M; Max-Delbrück-Center for Molecular Medicine, 13125 Berlin, Germany; Hematology, Oncology, and Tumor Immunology, Charité-Universitätsmedizin Berlin, 13353 Berlin, Germany;
  • Dörken B; Max-Delbrück-Center for Molecular Medicine, 13125 Berlin, Germany; Hematology, Oncology, and Tumor Immunology, Charité-Universitätsmedizin Berlin, 13353 Berlin, Germany; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany;
  • Bonifer C; School of Cancer Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, United Kingdom; c.bonifer@bham.ac.uk stephan.mathas@charite.de.
  • Mathas S; Max-Delbrück-Center for Molecular Medicine, 13125 Berlin, Germany; Hematology, Oncology, and Tumor Immunology, Charité-Universitätsmedizin Berlin, 13353 Berlin, Germany; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany; c.bonifer@bham.ac.uk stephan.mat
Proc Natl Acad Sci U S A ; 111(42): E4513-22, 2014 Oct 21.
Article em En | MEDLINE | ID: mdl-25288773
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Hodgkin / Cromatina / Fator de Transcrição AP-1 / Fatores Reguladores de Interferon Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Hodgkin / Cromatina / Fator de Transcrição AP-1 / Fatores Reguladores de Interferon Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2014 Tipo de documento: Article