SLC6A3 coding variant Ala559Val found in two autism probands alters dopamine transporter function and trafficking.

Bowton, E; Saunders, C; Reddy, I A; Campbell, N G; Hamilton, P J; Henry, L K; Coon, H; Sakrikar, D; Veenstra-VanderWeele, J M; Blakely, R D; Sutcliffe, J; Matthies, H J G; Erreger, K; Galli, A

Bowton, E; Saunders, C; Reddy, I A; Campbell, N G; Hamilton, P J; Henry, L K; Coon, H; Sakrikar, D; Veenstra-VanderWeele, J M; Blakely, R D; Sutcliffe, J; Matthies, H J G; Erreger, K; Galli, A.

Afiliação

Bowton E; 1] Departments of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, TN, USA [2] Vanderbilt Brain Institute, Vanderbilt University Medical Center, Nashville, TN, USA.
Saunders C; 1] Vanderbilt Brain Institute, Vanderbilt University Medical Center, Nashville, TN, USA [2] Department of Pharmacology, Vanderbilt University Medical Center, Nashville, TN, USA.
Reddy IA; 1] Departments of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, TN, USA [2] Vanderbilt Brain Institute, Vanderbilt University Medical Center, Nashville, TN, USA.
Campbell NG; 1] Departments of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, TN, USA [2] Vanderbilt Brain Institute, Vanderbilt University Medical Center, Nashville, TN, USA.
Hamilton PJ; 1] Departments of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, TN, USA [2] Vanderbilt Brain Institute, Vanderbilt University Medical Center, Nashville, TN, USA.
Henry LK; Department of Basic Sciences, University of North Dakota, Grand Forks, ND, USA.
Coon H; Department of Psychiatry, University of Utah, Salt Lake City, UT, USA.
Sakrikar D; 1] Vanderbilt Brain Institute, Vanderbilt University Medical Center, Nashville, TN, USA [2] Department of Pharmacology, Vanderbilt University Medical Center, Nashville, TN, USA.
Veenstra-VanderWeele JM; 1] Vanderbilt Brain Institute, Vanderbilt University Medical Center, Nashville, TN, USA [2] Department of Psychiatry, Vanderbilt University Medical Center, Nashville, TN, USA.
Blakely RD; 1] Vanderbilt Brain Institute, Vanderbilt University Medical Center, Nashville, TN, USA [2] Department of Pharmacology, Vanderbilt University Medical Center, Nashville, TN, USA.
Sutcliffe J; 1] Departments of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, TN, USA [2] Vanderbilt Brain Institute, Vanderbilt University Medical Center, Nashville, TN, USA [3] Department of Psychiatry, Vanderbilt University Medical Center, Nashville, TN, USA.
Matthies HJ; 1] Departments of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, TN, USA [2] Vanderbilt Brain Institute, Vanderbilt University Medical Center, Nashville, TN, USA [3] N-PISA Neuroscience Program In Substance Abuse, Vanderbilt University Medical Center, Nashville
Erreger K; 1] Departments of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, TN, USA [2] Vanderbilt Brain Institute, Vanderbilt University Medical Center, Nashville, TN, USA [3] N-PISA Neuroscience Program In Substance Abuse, Vanderbilt University Medical Center, Nashville
Galli A; 1] Departments of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, TN, USA [2] Vanderbilt Brain Institute, Vanderbilt University Medical Center, Nashville, TN, USA [3] N-PISA Neuroscience Program In Substance Abuse, Vanderbilt University Medical Center, Nashville

Transl Psychiatry ; 4: e464, 2014 Oct 14.

Article em En | MEDLINE | ID: mdl-25313507

Assuntos

Transtorno Autístico/genética; Proteínas da Membrana Plasmática de Transporte de Dopamina/genética; Mutação/genética; Transmissão Sináptica/genética; Movimento Celular/genética; Proteínas da Membrana Plasmática de Transporte de Dopamina/fisiologia; Humanos; Masculino; Irmãos

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtorno Autístico / Transmissão Sináptica / Proteínas da Membrana Plasmática de Transporte de Dopamina / Mutação Tipo de estudo: Prognostic_studies Limite: Humans / Male Idioma: En Revista: Transl Psychiatry Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos

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