Modulation of peroxisome proliferator-activated receptor-&#945; activity by bile acids causes circadian changes in the intestinal expression of Octn1/Slc22a4 in mice.

Wada, Erika; Koyanagi, Satoru; Kusunose, Naoki; Akamine, Takahiro; Masui, Hiroaki; Hashimoto, Hana; Matsunaga, Naoya; Ohdo, Shigehiro

Modulation of peroxisome proliferator-activated receptor-α activity by bile acids causes circadian changes in the intestinal expression of Octn1/Slc22a4 in mice.

Wada, Erika; Koyanagi, Satoru; Kusunose, Naoki; Akamine, Takahiro; Masui, Hiroaki; Hashimoto, Hana; Matsunaga, Naoya; Ohdo, Shigehiro.

Afiliação

Wada E; Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Koyanagi S; Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Kusunose N; Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Akamine T; Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Masui H; Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Hashimoto H; Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Matsunaga N; Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Ohdo S; Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan ohdo@phar.kyushu-u.ac.jp.

Mol Pharmacol ; 87(2): 314-22, 2015 Feb.

Article em En | MEDLINE | ID: mdl-25422143

Assuntos

Ácidos e Sais Biliares/farmacologia; Proteínas de Transporte/biossíntese; Ritmo Circadiano/fisiologia; Regulação da Expressão Gênica; Mucosa Intestinal/metabolismo; Proteínas de Membrana/biossíntese; PPAR alfa/metabolismo; Animais; Células CACO-2; Ritmo Circadiano/efeitos dos fármacos; Humanos; Mucosa Intestinal/efeitos dos fármacos; Masculino; Camundongos; Camundongos Endogâmicos ICR; Camundongos Knockout; Proteínas de Transporte de Cátions Orgânicos; Simportadores

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácidos e Sais Biliares / Proteínas de Transporte / Regulação da Expressão Gênica / Ritmo Circadiano / PPAR alfa / Mucosa Intestinal / Proteínas de Membrana Tipo de estudo: Etiology_studies Limite: Animals / Humans / Male Idioma: En Revista: Mol Pharmacol Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Japão

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