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The constitutive activation of Egr-1/C/EBPa mediates the development of type 2 diabetes mellitus by enhancing hepatic gluconeogenesis.
Shen, Ning; Jiang, Shan; Lu, Jia-Ming; Yu, Xiao; Lai, Shan-Shan; Zhang, Jing-Zi; Zhang, Jin-Long; Tao, Wei-Wei; Wang, Xiu-Xing; Xu, Na; Xue, Bin; Li, Chao-Jun.
Afiliação
  • Shen N; Ministry of Education Key Laboratory of Model Animals for Disease Study, Model Animal Research Center and the Medical School of Nanjing University, National Resource Center for Mutant Mice, Nanjing, China.
  • Jiang S; Ministry of Education Key Laboratory of Model Animals for Disease Study, Model Animal Research Center and the Medical School of Nanjing University, National Resource Center for Mutant Mice, Nanjing, China.
  • Lu JM; Ministry of Education Key Laboratory of Model Animals for Disease Study, Model Animal Research Center and the Medical School of Nanjing University, National Resource Center for Mutant Mice, Nanjing, China.
  • Yu X; Ministry of Education Key Laboratory of Model Animals for Disease Study, Model Animal Research Center and the Medical School of Nanjing University, National Resource Center for Mutant Mice, Nanjing, China.
  • Lai SS; Ministry of Education Key Laboratory of Model Animals for Disease Study, Model Animal Research Center and the Medical School of Nanjing University, National Resource Center for Mutant Mice, Nanjing, China.
  • Zhang JZ; Ministry of Education Key Laboratory of Model Animals for Disease Study, Model Animal Research Center and the Medical School of Nanjing University, National Resource Center for Mutant Mice, Nanjing, China.
  • Zhang JL; Ministry of Education Key Laboratory of Model Animals for Disease Study, Model Animal Research Center and the Medical School of Nanjing University, National Resource Center for Mutant Mice, Nanjing, China.
  • Tao WW; Ministry of Education Key Laboratory of Model Animals for Disease Study, Model Animal Research Center and the Medical School of Nanjing University, National Resource Center for Mutant Mice, Nanjing, China.
  • Wang XX; Ministry of Education Key Laboratory of Model Animals for Disease Study, Model Animal Research Center and the Medical School of Nanjing University, National Resource Center for Mutant Mice, Nanjing, China.
  • Xu N; Ministry of Education Key Laboratory of Model Animals for Disease Study, Model Animal Research Center and the Medical School of Nanjing University, National Resource Center for Mutant Mice, Nanjing, China.
  • Xue B; Ministry of Education Key Laboratory of Model Animals for Disease Study, Model Animal Research Center and the Medical School of Nanjing University, National Resource Center for Mutant Mice, Nanjing, China. Electronic address: xuebin@nju.edu.cn.
  • Li CJ; Ministry of Education Key Laboratory of Model Animals for Disease Study, Model Animal Research Center and the Medical School of Nanjing University, National Resource Center for Mutant Mice, Nanjing, China. Electronic address: licj@nju.edu.cn.
Am J Pathol ; 185(2): 513-23, 2015 Feb.
Article em En | MEDLINE | ID: mdl-25438063
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Estimuladoras de Ligação a CCAAT / Diabetes Mellitus Experimental / Diabetes Mellitus Tipo 2 / Proteína 1 de Resposta de Crescimento Precoce / Gluconeogênese / Fígado Limite: Animals Idioma: En Revista: Am J Pathol Ano de publicação: 2015 Tipo de documento: Article País de afiliação: China
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Estimuladoras de Ligação a CCAAT / Diabetes Mellitus Experimental / Diabetes Mellitus Tipo 2 / Proteína 1 de Resposta de Crescimento Precoce / Gluconeogênese / Fígado Limite: Animals Idioma: En Revista: Am J Pathol Ano de publicação: 2015 Tipo de documento: Article País de afiliação: China