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Hepatitis C virus infection induces autocrine interferon signaling by human liver endothelial cells and release of exosomes, which inhibits viral replication.
Giugliano, Silvia; Kriss, Michael; Golden-Mason, Lucy; Dobrinskikh, Evgenia; Stone, Amy E L; Soto-Gutierrez, Alejandro; Mitchell, Angela; Khetani, Salman R; Yamane, Daisuke; Stoddard, Mark; Li, Hui; Shaw, George M; Edwards, Michael G; Lemon, Stanley M; Gale, Michael; Shah, Vijay H; Rosen, Hugo R.
Afiliação
  • Giugliano S; Division of Gastroenterology and Hepatology, Hepatitis C Center, Department of Medicine, University of Colorado, Denver, Aurora, Colorado.
  • Kriss M; Division of Gastroenterology and Hepatology, Hepatitis C Center, Department of Medicine, University of Colorado, Denver, Aurora, Colorado.
  • Golden-Mason L; Division of Gastroenterology and Hepatology, Hepatitis C Center, Department of Medicine, University of Colorado, Denver, Aurora, Colorado; Integrated Department in Immunology: University of Colorado Denver and National Jewish Health, Denver, Colorado.
  • Dobrinskikh E; Division of Renal Diseases and Hypertension, Department of Medicine, University of Colorado Denver, Aurora, Colorado.
  • Stone AE; Department of Immunology, University of Washington, School of Medicine, Seattle, Washington.
  • Soto-Gutierrez A; Department of Pathology, Center for Innovative Regenerative Therapies, Department of Surgery, Transplantation Section, Children's Hospital of Pittsburgh, McGowan Institute for Regenerative Medicine and the Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, Pennsylvania.
  • Mitchell A; Division of Gastroenterology and Hepatology, Hepatitis C Center, Department of Medicine, University of Colorado, Denver, Aurora, Colorado; Integrated Department in Immunology: University of Colorado Denver and National Jewish Health, Denver, Colorado.
  • Khetani SR; Mechanical and Biomedical Engineering, Colorado State University, Fort Collins, Colorado.
  • Yamane D; Department of Medicine, University of North Carolina, Chapel Hill, North Carolina.
  • Stoddard M; Department of Medicine and Microbiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania.
  • Li H; Department of Medicine and Microbiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania.
  • Shaw GM; Department of Medicine and Microbiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania.
  • Edwards MG; Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado Denver, Aurora, Colorado.
  • Lemon SM; Department of Medicine, University of North Carolina, Chapel Hill, North Carolina.
  • Gale M; Department of Immunology, University of Washington, School of Medicine, Seattle, Washington.
  • Shah VH; Mayo Clinic, Division of Gastroenterology and Hepatology, Rochester, Minnesota.
  • Rosen HR; Division of Gastroenterology and Hepatology, Hepatitis C Center, Department of Medicine, University of Colorado, Denver, Aurora, Colorado; Integrated Department in Immunology: University of Colorado Denver and National Jewish Health, Denver, Colorado; Eastern Colorado Veteran's Affairs Medical Cente
Gastroenterology ; 148(2): 392-402.e13, 2015 Feb.
Article em En | MEDLINE | ID: mdl-25447848
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Replicação Viral / Interferons / Hepacivirus / Comunicação Autócrina / Células Endoteliais / Exossomos / Fígado Limite: Humans Idioma: En Revista: Gastroenterology Ano de publicação: 2015 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Replicação Viral / Interferons / Hepacivirus / Comunicação Autócrina / Células Endoteliais / Exossomos / Fígado Limite: Humans Idioma: En Revista: Gastroenterology Ano de publicação: 2015 Tipo de documento: Article