The mouse hindbrain: an in vivo model to analyze developmental angiogenesis.
Methods Mol Biol
; 1214: 29-40, 2015.
Article
em En
| MEDLINE
| ID: mdl-25468597
ABSTRACT
Angiogenesis, defined as the sprouting of new blood vessels from preexisting ones, is a biological process of great clinical relevance due to its involvement in disease as well as its therapeutic potential for revascularizing ischemic tissues. The embryonic mouse hindbrain provides an excellent model to study the molecular and cellular mechanisms of angiogenesis in vivo due the simple geometry of the hindbrain vasculature and its easy accessibility for fluorescent or histochemical staining, and for image capture and quantitation. This chapter outlines protocols for dissection, staining, and analysis of the mouse embryo hindbrain vasculature.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Rombencéfalo
/
Neovascularização Fisiológica
Tipo de estudo:
Guideline
Limite:
Animals
/
Pregnancy
Idioma:
En
Revista:
Methods Mol Biol
Assunto da revista:
BIOLOGIA MOLECULAR
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
Reino Unido