Long-term potentiation in the motor cortex.
Science
; 245(4924): 1385-7, 1989 Sep 22.
Article
em En
| MEDLINE
| ID: mdl-2551038
ABSTRACT
Long-term potentiation (LTP) is a model for learning and memory processes. Tetanic stimulation of the sensory cortex produces LTP in motor cortical neurons, whereas tetanization of the ventrolateral nucleus of the thalamus, which also projects to the motor cortex, does not. However, after simultaneous high-frequency stimulation of both the sensory cortex and the ventrolateral nucleus of the thalamus, LTP of thalamic input to motor cortical neurons is induced. This associative LTP occurs only in neurons in the superficial layers of the motor cortex that receive monosynaptic input from both the sensory cortex and the ventrolateral nucleus of the thalamus. Associative LTP in the motor cortex may constitute a basis for the retention of motor skills.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Córtex Motor
/
Destreza Motora
Limite:
Animals
Idioma:
En
Revista:
Science
Ano de publicação:
1989
Tipo de documento:
Article