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Computational modeling predicts IL-10 control of lesion sterilization by balancing early host immunity-mediated antimicrobial responses with caseation during mycobacterium tuberculosis infection.
Cilfone, Nicholas A; Ford, Christopher B; Marino, Simeone; Mattila, Joshua T; Gideon, Hannah P; Flynn, JoAnne L; Kirschner, Denise E; Linderman, Jennifer J.
Afiliação
  • Cilfone NA; Department of Chemical Engineering, University of Michigan, Ann Arbor, MI 48109;
  • Ford CB; Broad Institute of MIT and Harvard, Cambridge, MA 02142;
  • Marino S; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI 48109; and.
  • Mattila JT; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219.
  • Gideon HP; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219.
  • Flynn JL; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219.
  • Kirschner DE; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI 48109; and.
  • Linderman JJ; Department of Chemical Engineering, University of Michigan, Ann Arbor, MI 48109; linderma@umich.edu.
J Immunol ; 194(2): 664-77, 2015 Jan 15.
Article em En | MEDLINE | ID: mdl-25512604
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tuberculose / Interleucina-10 / Ativação de Macrófagos / Macrófagos / Mycobacterium tuberculosis Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: J Immunol Ano de publicação: 2015 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tuberculose / Interleucina-10 / Ativação de Macrófagos / Macrófagos / Mycobacterium tuberculosis Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: J Immunol Ano de publicação: 2015 Tipo de documento: Article