Synthesis, characterization and in vitro photodynamic antimicrobial activity of basic amino acid-porphyrin conjugates.

Meng, Shuai; Xu, Zengping; Hong, Ge; Zhao, Lihui; Zhao, Zhanjuan; Guo, Jianghong; Ji, Haiying; Liu, Tianjun

Meng, Shuai; Xu, Zengping; Hong, Ge; Zhao, Lihui; Zhao, Zhanjuan; Guo, Jianghong; Ji, Haiying; Liu, Tianjun.

Afiliação

Meng S; Institute of Biomedical Engineering, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin Key Laboratory of Biomedical Material, Tianjin 300192, China.
Xu Z; Institute of Biomedical Engineering, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin Key Laboratory of Biomedical Material, Tianjin 300192, China.
Hong G; Institute of Biomedical Engineering, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin Key Laboratory of Biomedical Material, Tianjin 300192, China.
Zhao L; Institute of Biomedical Engineering, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin Key Laboratory of Biomedical Material, Tianjin 300192, China.
Zhao Z; Institute of Biomedical Engineering, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin Key Laboratory of Biomedical Material, Tianjin 300192, China.
Guo J; Institute of Biomedical Engineering, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin Key Laboratory of Biomedical Material, Tianjin 300192, China.
Ji H; Institute of Biomedical Engineering, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin Key Laboratory of Biomedical Material, Tianjin 300192, China.
Liu T; Institute of Biomedical Engineering, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin Key Laboratory of Biomedical Material, Tianjin 300192, China. Electronic address: liutianjun@hotmail.com.

Eur J Med Chem ; 92: 35-48, 2015 Mar 06.

Article em En | MEDLINE | ID: mdl-25544685

Assuntos

Aminoácidos/farmacologia; Antibacterianos/farmacologia; Escherichia coli/efeitos dos fármacos; Staphylococcus aureus Resistente à Meticilina/efeitos dos fármacos; Fármacos Fotossensibilizantes/farmacologia; Porfirinas/farmacologia; Pseudomonas aeruginosa/efeitos dos fármacos; Aminoácidos/química; Antibacterianos/síntese química; Antibacterianos/química; Linhagem Celular; Relação Dose-Resposta a Droga; Humanos; Testes de Sensibilidade Microbiana; Fármacos Fotossensibilizantes/síntese química; Fármacos Fotossensibilizantes/química; Porfirinas/química; Relação Estrutura-Atividade

Palavras-chave

Basic amino acid; Cationic porphyrins; Photodynamic antimicrobial chemotherapy; Photosensitizer

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Porfirinas / Pseudomonas aeruginosa / Fármacos Fotossensibilizantes / Escherichia coli / Staphylococcus aureus Resistente à Meticilina / Aminoácidos / Antibacterianos Limite: Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2015 Tipo de documento: Article País de afiliação: China

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google