Your browser doesn't support javascript.
loading
Determining the persistence of maternally acquired antibodies to hepatitis A and varicella zoster during the first 2 years of life in Turkey.
Begde, Firat; Orhon, Filiz Simsek; Gerceker, Devran; Ulukol, Betul; Topcu, Seda; Baskan, Sevgi.
Afiliação
  • Begde F; Department of Pediatrics, Division of Social Pediatrics, Ankara University Faculty of Medicine, Dikimevi, Ankara, Turkey, dr_ogu72@hotmail.com.
Eur J Pediatr ; 174(7): 883-90, 2015 Jul.
Article em En | MEDLINE | ID: mdl-25563217
UNLABELLED: Vaccination should be timed to take into account the potential interference of maternal antibodies. The purpose of this study was to determine the persistence of maternally acquired antibodies to hepatitis A and varicella zoster in a group of healthy infants between 6 and 24 months of age. These infants were divided into four groups according to the age at the time of follow-up visits. The study group consisted of infants who were brought to the 6-month follow-up visit (group 1, n=100), 12-month follow-up visit (group 2, n=99), 18-month follow-up visit (group 3, n=59), and 24-month follow-up visit (group 4, n=59). Hepatitis A, varicella IgG, and IgM antibodies were analyzed qualitatively. Hepatitis A IgG seropositivity was determined as 71 % in group 1, 41.4 % in group 2, 0 % in group 3, and 8.5 % in group 4 (p<0.001). Varicella IgG seropositivity was found to be 5 % in group 1, 4 % in group 2, 4 % in group 3, and 1 % in group 4 (p>0.05). CONCLUSION: We found that maternal hepatitis A antibodies in children disappear between 12 and 18 months, whereas maternal varicella antibodies substantially diminish following the sixth month. Therefore, the vaccination timing should be based on factors such as the interference of maternal antibodies, disease susceptibility period, and immune maturation.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Herpesvirus Humano 3 / Anticorpos Anti-Hepatite A / Imunidade Materno-Adquirida / Anticorpos Antivirais Limite: Child, preschool / Female / Humans / Infant / Male País/Região como assunto: Asia Idioma: En Revista: Eur J Pediatr Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Herpesvirus Humano 3 / Anticorpos Anti-Hepatite A / Imunidade Materno-Adquirida / Anticorpos Antivirais Limite: Child, preschool / Female / Humans / Infant / Male País/Região como assunto: Asia Idioma: En Revista: Eur J Pediatr Ano de publicação: 2015 Tipo de documento: Article