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[Potential targets for anti-liver fibrosis].
Zhao, Shuang-shuang; Shao, Rong-guang; He, Hong-wei.
Afiliação
  • Zhao SS; Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Yao Xue Xue Bao ; 49(10): 1365-71, 2014 Oct.
Article em Zh | MEDLINE | ID: mdl-25577864
Liver fibrosis is a pathological process of the excessive accumulation of extracellular matrix, especially collagen al (I) in liver. Ultimately, hepatic fibrosis leads to cirrhosis or hepatic failure. Liver fibrosis and early cirrhosis can be reversed, thus control of the development of liver fibrosis is very important for preventive treatment of cirrhosis and hepatic failure. This is a review of potential targets for anti-hepatic fibrosis based on plenty of publications, including TGF-ß1 and integrin α(v) and so on, aimed at providing novel therapeutic targets in liver fibrosis.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cirrose Hepática Limite: Humans Idioma: Zh Revista: Yao Xue Xue Bao Ano de publicação: 2014 Tipo de documento: Article País de afiliação: China
Buscar no Google
Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cirrose Hepática Limite: Humans Idioma: Zh Revista: Yao Xue Xue Bao Ano de publicação: 2014 Tipo de documento: Article País de afiliação: China