Epoxyeicosatrienoic acids regulate macrophage polarization and prevent LPS-induced cardiac dysfunction.

Dai, Meiyan; Wu, Lujin; He, Zuowen; Zhang, Shasha; Chen, Chen; Xu, Xizhen; Wang, Peihua; Gruzdev, Artiom; Zeldin, Darryl C; Wang, Dao Wen

Dai, Meiyan; Wu, Lujin; He, Zuowen; Zhang, Shasha; Chen, Chen; Xu, Xizhen; Wang, Peihua; Gruzdev, Artiom; Zeldin, Darryl C; Wang, Dao Wen.

Afiliação

Dai M; Departments of Internal Medicine and Institute of Hypertension, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wu L; Departments of Internal Medicine and Institute of Hypertension, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
He Z; Departments of Internal Medicine and Institute of Hypertension, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Zhang S; Departments of Internal Medicine and Institute of Hypertension, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Chen C; Departments of Internal Medicine and Institute of Hypertension, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Xu X; Departments of Internal Medicine and Institute of Hypertension, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wang P; Departments of Internal Medicine and Institute of Hypertension, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Gruzdev A; Division of Intramural Research, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, North Carolina.
Zeldin DC; Division of Intramural Research, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, North Carolina.
Wang DW; Departments of Internal Medicine and Institute of Hypertension, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

J Cell Physiol ; 230(9): 2108-19, 2015 Sep.

Article em En | MEDLINE | ID: mdl-25626689

Assuntos

Ácido 8,11,14-Eicosatrienoico/administração & dosagem; Sistema Enzimático do Citocromo P-450/biossíntese; Inflamação/genética; Miocárdio/metabolismo; Ácido 8,11,14-Eicosatrienoico/análogos & derivados; Animais; Polaridade Celular/genética; Citocromo P-450 CYP2J2; Sistema Enzimático do Citocromo P-450/genética; Sistema Enzimático do Citocromo P-450/metabolismo; Sistema Enzimático do Citocromo P-450/uso terapêutico; Regulação da Expressão Gênica/genética; Heme Oxigenase-1/genética; Inflamação/induzido quimicamente; Inflamação/terapia; Lipopolissacarídeos/toxicidade; Macrófagos/metabolismo; Macrófagos/patologia; Camundongos; Miocárdio/patologia; NF-kappa B/genética; NF-kappa B/metabolismo; PPAR alfa/genética; PPAR alfa/metabolismo; PPAR gama/genética; Transdução de Sinais/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sistema Enzimático do Citocromo P-450 / Ácido 8,11,14-Eicosatrienoico / Inflamação / Miocárdio Limite: Animals Idioma: En Revista: J Cell Physiol Ano de publicação: 2015 Tipo de documento: Article País de afiliação: China

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