Nectin-like interactions between poliovirus and its receptor trigger conformational changes associated with cell entry.

Strauss, Mike; Filman, David J; Belnap, David M; Cheng, Naiqian; Noel, Roane T; Hogle, James M

Strauss, Mike; Filman, David J; Belnap, David M; Cheng, Naiqian; Noel, Roane T; Hogle, James M.

Afiliação

Strauss M; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, USA.
Filman DJ; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, USA.
Belnap DM; Laboratory of Structural Biology Research, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, USA Department of Chemistry and Biochemistry, Brigham Young University, Provo, Utah, USA Departments of Biology and Biochemistry, Unive
Cheng N; Laboratory of Structural Biology Research, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Noel RT; Department of Chemistry and Biochemistry, Brigham Young University, Provo, Utah, USA.
Hogle JM; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, USA james_hogle@hms.harvard.edu.

J Virol ; 89(8): 4143-57, 2015 Apr.

Article em En | MEDLINE | ID: mdl-25631086

Assuntos

Moléculas de Adesão Celular/metabolismo; Modelos Moleculares; Conformação de Ácido Nucleico; Poliovirus/química; Poliovirus/fisiologia; Receptores Virais/química; Receptores Virais/metabolismo; Internalização do Vírus; Proteínas do Capsídeo/química; Proteínas do Capsídeo/metabolismo; Microscopia Crioeletrônica; Células HeLa; Humanos; Nectinas; Poliovirus/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores Virais / Modelos Moleculares / Moléculas de Adesão Celular / Poliovirus / Internalização do Vírus / Conformação de Ácido Nucleico Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: J Virol Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos

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