[Anti-NR1 antibodies in anti-N-methyl-D-aspartate receptor encephalitis and schizophrenia]. / Anticorps anti-NR1 dans l'encéphalite anti-récepteur N-méthyl-D-aspartate et la schizophrénie.
Med Sci (Paris)
; 31(1): 60-7, 2015 Jan.
Article
em Fr
| MEDLINE
| ID: mdl-25658732
ABSTRACT
The recent discovery of anti-NMDA receptor antibodies and proof of their pathogenic effects in limbic encephalitides raised many questions among neuroscientist and physicians working in the field of schizophrenia. Indeed, this two conditions share several major clinical, pathophysiological or etiological aspects and some authors tend to consider some forms of schizophrenia as mild-encephalitis cases. Some studies have reported the presence of these antibodies in schizophrenic patient's sera without neurological symptoms. These findings suggest new therapeutic perspectives in some schizophrenic patients, despite a low seroprevalence and pathogenic effects that remain to be demonstrated.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Esquizofrenia
/
Autoanticorpos
/
Receptores de N-Metil-D-Aspartato
/
Encefalite Antirreceptor de N-Metil-D-Aspartato
Limite:
Humans
Idioma:
Fr
Revista:
Med Sci (Paris)
Assunto da revista:
MEDICINA
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
França