Toxicities associated with NBOMe ingestion-a novel class of potent hallucinogens: a review of the literature.
Psychosomatics
; 56(2): 129-39, 2015.
Article
em En
| MEDLINE
| ID: mdl-25659919
ABSTRACT
BACKGROUND:
A new class of synthetic hallucinogens called NBOMe has emerged as drugs of abuse.OBJECTIVE:
Our aim was to conduct a systematic review of published reports of toxicities associated with NBOMe ingestion.METHODS:
We searched PubMed for relevant English-language citations that described adverse effects from analytically confirmed human NBOMe ingestion. Demographic and clinical data were extracted.RESULTS:
A total of 10 citations met the criteria for inclusion, representing 20 individual patients. 25I-NBOMe was the most common analogue identified, followed by 25B-NBOMe and 25C-NBOMe. Fatalities were reported in 3 (15%) cases. Of all the patients, 7 (35%) were discharged after a period of observation, whereas 8 (40.0%) required admission to an intensive care unit. The most common adverse effects were agitation (85.0%), tachycardia (85.0%), and hypertension (65.0%). Seizures were reported in 8 (40.0%) patients. The most common abnormalities reported on laboratory tests were elevated level of creatinine kinase (45.0%), leukocytosis (25.0%), and hyperglycemia (20.0%).CONCLUSION:
NBOMe ingestion is associated with severe adverse effects. Clinicians need to have a high index of suspicion for NBOMe ingestion in patients reporting the recent use of hallucinogens.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Convulsões
/
Taquicardia
/
Alucinógenos
/
Hiperglicemia
/
Hipertensão
/
Leucocitose
Tipo de estudo:
Prognostic_studies
/
Risk_factors_studies
/
Systematic_reviews
Limite:
Humans
Idioma:
En
Revista:
Psychosomatics
Ano de publicação:
2015
Tipo de documento:
Article