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Heterozygosity for the common perforin mutation, p.A91V, impairs the cytotoxicity of primary natural killer cells from healthy individuals.
House, Imran G; Thia, Kevin; Brennan, Amelia J; Tothill, Richard; Dobrovic, Alexander; Yeh, Wei Z; Saffery, Richard; Chatterton, Zac; Trapani, Joseph A; Voskoboinik, Ilia.
Afiliação
  • House IG; 1] Cancer Immunology Program, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia [2] Sir Peter MacCallum Department of Oncology, Parkville, Victoria, Australia [3] Department of Pathology, University of Melbourne, Parkville, Victoria, Australia.
  • Thia K; Cancer Immunology Program, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia.
  • Brennan AJ; Cancer Immunology Program, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia.
  • Tothill R; 1] Cancer Immunology Program, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia [2] Department of Pathology, University of Melbourne, Parkville, Victoria, Australia.
  • Dobrovic A; Ludwig Institute for Cancer Research, Olivia Newton-John Cancer and Wellness Centre, Heidelberg (Melbourne), Victoria, Australia.
  • Yeh WZ; Cancer Immunology Program, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia.
  • Saffery R; Murdoch Children's Research Institute; Department of Paediatrics; The University of Melbourne; Royal Children's Hospital, Melbourne, Victoria, Australia.
  • Chatterton Z; Murdoch Children's Research Institute; Department of Paediatrics; The University of Melbourne; Royal Children's Hospital, Melbourne, Victoria, Australia.
  • Trapani JA; 1] Cancer Immunology Program, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia [2] Sir Peter MacCallum Department of Oncology, Parkville, Victoria, Australia [3] Department of Pathology, University of Melbourne, Parkville, Victoria, Australia [4] Department of Immunology and Microb
  • Voskoboinik I; 1] Cancer Immunology Program, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia [2] Sir Peter MacCallum Department of Oncology, Parkville, Victoria, Australia [3] Department of Pathology, University of Melbourne, Parkville, Victoria, Australia [4] Department of Genetics, University
Immunol Cell Biol ; 93(6): 575-80, 2015 Jul.
Article em En | MEDLINE | ID: mdl-25776844
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células Matadoras Naturais / Citotoxicidade Imunológica / Perforina / Heterozigoto / Mutação Limite: Humans Idioma: En Revista: Immunol Cell Biol Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Austrália
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células Matadoras Naturais / Citotoxicidade Imunológica / Perforina / Heterozigoto / Mutação Limite: Humans Idioma: En Revista: Immunol Cell Biol Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Austrália