Your browser doesn't support javascript.
loading
Pharmacokinetics (PK), pharmacodynamics (PD) and integrated PK/PD modeling of a novel long acting FGF21 clinical candidate PF-05231023 in diet-induced obese and leptin-deficient obese mice.
Weng, Yan; Chabot, Jeffrey R; Bernardo, Barbara; Yan, Qingyun; Zhu, Yimin; Brenner, Martin B; Vage, Chandra; Logan, Alison; Calle, Roberto; Talukdar, Saswata.
Afiliação
  • Weng Y; Cardiovascular Metabolic and Endocrine Diseases (CVMED) Research Unit, Pfizer Worldwide Research & Development, 610 Main Street, Cambridge, Massachusetts, 02139, United States of America; Pharmacokinetics, Dynamics, and Metabolism, Pfizer Worldwide Research & Development, 610 Main Street, Ca
  • Chabot JR; Cardiovascular Metabolic and Endocrine Diseases (CVMED) Research Unit, Pfizer Worldwide Research & Development, 610 Main Street, Cambridge, Massachusetts, 02139, United States of America; Pharmacokinetics, Dynamics, and Metabolism, Pfizer Worldwide Research & Development, 610 Main Street, Ca
  • Bernardo B; Cardiovascular Metabolic and Endocrine Diseases (CVMED) Research Unit, Pfizer Worldwide Research & Development, 610 Main Street, Cambridge, Massachusetts, 02139, United States of America.
  • Yan Q; Cardiovascular Metabolic and Endocrine Diseases (CVMED) Research Unit, Pfizer Worldwide Research & Development, 610 Main Street, Cambridge, Massachusetts, 02139, United States of America.
  • Zhu Y; Cardiovascular Metabolic and Endocrine Diseases (CVMED) Research Unit, Pfizer Worldwide Research & Development, 610 Main Street, Cambridge, Massachusetts, 02139, United States of America.
  • Brenner MB; Cardiovascular Metabolic and Endocrine Diseases (CVMED) Research Unit, Pfizer Worldwide Research & Development, 610 Main Street, Cambridge, Massachusetts, 02139, United States of America.
  • Vage C; Pharmacokinetics, Dynamics, and Metabolism, Pfizer Worldwide Research & Development, 610 Main Street, Cambridge, Massachusetts, 02139, United States of America.
  • Logan A; Cardiovascular Metabolic and Endocrine Diseases (CVMED) Research Unit, Pfizer Worldwide Research & Development, 610 Main Street, Cambridge, Massachusetts, 02139, United States of America.
  • Calle R; Cardiovascular Metabolic and Endocrine Diseases (CVMED) Research Unit, Pfizer Worldwide Research & Development, 610 Main Street, Cambridge, Massachusetts, 02139, United States of America.
  • Talukdar S; Cardiovascular Metabolic and Endocrine Diseases (CVMED) Research Unit, Pfizer Worldwide Research & Development, 610 Main Street, Cambridge, Massachusetts, 02139, United States of America.
PLoS One ; 10(3): e0119104, 2015.
Article em En | MEDLINE | ID: mdl-25790234
Assuntos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leptina / Anticorpos Monoclonais Humanizados / Fatores de Crescimento de Fibroblastos / Modelos Biológicos / Obesidade Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Canadá
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leptina / Anticorpos Monoclonais Humanizados / Fatores de Crescimento de Fibroblastos / Modelos Biológicos / Obesidade Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Canadá