Polyphenol extract from Phellinus igniarius protects against acrolein toxicity in vitro and provides protection in a mouse stroke model.

Suabjakyong, Papawee; Saiki, Ryotaro; Van Griensven, Leo J L D; Higashi, Kyohei; Nishimura, Kazuhiro; Igarashi, Kazuei; Toida, Toshihiko

Suabjakyong, Papawee; Saiki, Ryotaro; Van Griensven, Leo J L D; Higashi, Kyohei; Nishimura, Kazuhiro; Igarashi, Kazuei; Toida, Toshihiko.

Afiliação

Suabjakyong P; Department of Clinical and Analytical Biochemistry, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba-shi, Chiba, Japan.
Saiki R; Department of Clinical and Analytical Biochemistry, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba-shi, Chiba, Japan; Amine Pharma Research Institute, Innovation Plaza at Chiba University, Chiba-shi, Chiba, Japan.
Van Griensven LJ; Plant Research International, Wageningen University and Research Centre, Wageningen, The Netherlands.
Higashi K; Department of Clinical and Analytical Biochemistry, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba-shi, Chiba, Japan.
Nishimura K; Department of Clinical and Analytical Biochemistry, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba-shi, Chiba, Japan.
Igarashi K; Department of Clinical and Analytical Biochemistry, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba-shi, Chiba, Japan; Amine Pharma Research Institute, Innovation Plaza at Chiba University, Chiba-shi, Chiba, Japan.
Toida T; Department of Clinical and Analytical Biochemistry, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba-shi, Chiba, Japan.

PLoS One ; 10(3): e0122733, 2015.

Article em En | MEDLINE | ID: mdl-25811373

Assuntos

Acroleína/toxicidade; Antioxidantes/farmacologia; Basidiomycota/química; Polifenóis/farmacologia; Substâncias Protetoras/farmacologia; Acidente Vascular Cerebral/etiologia; Acidente Vascular Cerebral/metabolismo; Animais; Antioxidantes/química; Linhagem Celular; Modelos Animais de Doenças; Poluentes Ambientais/toxicidade; Peróxido de Hidrogênio/metabolismo; Masculino; Camundongos; Polifenóis/química; Substâncias Protetoras/química; Acidente Vascular Cerebral/tratamento farmacológico; Acidente Vascular Cerebral/patologia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Basidiomycota / Acroleína / Substâncias Protetoras / Acidente Vascular Cerebral / Polifenóis / Antioxidantes Limite: Animals Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Japão

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