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Novel dosing strategies increase exposures of the potent antituberculosis drug rifapentine but are poorly tolerated in healthy volunteers.
Dooley, Kelly E; Savic, Radojka M; Park, Jeong-Gun; Cramer, Yoninah; Hafner, Richard; Hogg, Evelyn; Janik, Jennifer; Marzinke, Mark A; Patterson, Kristine; Benson, Constance A; Hovind, Laura; Dorman, Susan E; Haas, David W.
Afiliação
  • Dooley KE; Johns Hopkins University School of Medicine, Baltimore, Maryland, USA kdooley1@jhmi.edu.
  • Savic RM; University of California, San Francisco, California, USA.
  • Park JG; Center for Biostatistics in AIDS Research, Harvard School of Public Health, Boston, Massachusetts, USA.
  • Cramer Y; Center for Biostatistics in AIDS Research, Harvard School of Public Health, Boston, Massachusetts, USA.
  • Hafner R; Division of AIDS, National Institutes of Health, Bethesda, Maryland, USA.
  • Hogg E; Social & Scientific Systems, Inc., Silver Spring, Maryland, USA.
  • Janik J; Frontier Science Foundation, Amherst, New York, USA.
  • Marzinke MA; Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Patterson K; University of North Carolina, Chapel Hill, North Carolina, USA.
  • Benson CA; University of California, San Diego, California, USA.
  • Hovind L; Frontier Science Foundation, Amherst, New York, USA.
  • Dorman SE; Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Haas DW; Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Antimicrob Agents Chemother ; 59(6): 3399-405, 2015.
Article em En | MEDLINE | ID: mdl-25824215

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Rifampina / Antituberculosos Tipo de estudo: Clinical_trials / Guideline Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Antimicrob Agents Chemother Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Rifampina / Antituberculosos Tipo de estudo: Clinical_trials / Guideline Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Antimicrob Agents Chemother Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos