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MDM2 antagonist clinical response association with a gene expression signature in acute myeloid leukaemia.
Zhong, Hua; Chen, Gong; Jukofsky, Lori; Geho, David; Han, Sung Won; Birzele, Fabian; Bader, Sabine; Himmelein, Lucia; Cai, James; Albertyn, Zayed; Rothe, Mark; Essioux, Laurent; Burtscher, Helmut; Middleton, Steven A; Rueger, Ruediger; Chen, Lin-Chi; Dangl, Markus; Nichols, Gwen; Pierceall, William E.
Afiliação
  • Zhong H; Pharmaceutical Sciences, Roche Pharmaceutical Research and Early Development, Roche Innovation Center New York, New York, NY, USA. hua.zhong@roche.com.
  • Chen G; Pharmaceutical Sciences, Roche Pharmaceutical Research and Early Development, Roche Innovation Center New York, New York, NY, USA.
  • Jukofsky L; Translational Medicine Oncology, Roche Pharmaceutical Research and Early Development, Roche Innovation Center New York, New York, NY, USA.
  • Geho D; Translational Medicine Oncology, Roche Pharmaceutical Research and Early Development, Roche Innovation Center New York, New York, NY, USA.
  • Han SW; Division of Biostatistics, Departments of Population Health, New York University School of Medicine, New York, NY, USA.
  • Birzele F; Pharmaceutical Sciences, Roche Pharmaceutical Research and Early Development, Roche Innovation Center Penzberg, Penzberg, Germany.
  • Bader S; Pharmaceutical Sciences, Roche Pharmaceutical Research and Early Development, Roche Innovation Center Penzberg, Penzberg, Germany.
  • Himmelein L; Pharmaceutical Sciences, Roche Pharmaceutical Research and Early Development, Roche Innovation Center Penzberg, Penzberg, Germany.
  • Cai J; Informatics, Roche Pharmaceutical Research and Early Development, Roche Innovation Center New York, New York, NY, USA.
  • Albertyn Z; Informatics, Roche Pharmaceutical Research and Early Development, Roche Innovation Center New York, New York, NY, USA.
  • Rothe M; Biometrics, Product Development, Roche Innovation Center New York, New York, NY, USA.
  • Essioux L; Pharmaceutical Sciences, Roche Pharmaceutical Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.
  • Burtscher H; Discovery Oncology, Roche Pharmaceutical Research and Early Development, Roche Innovation Center Penzberg, Penzberg, Germany.
  • Middleton SA; Translational Medicine Oncology, Roche Pharmaceutical Research and Early Development, Roche Innovation Center New York, New York, NY, USA.
  • Rueger R; Translational Medicine Oncology, Roche Pharmaceutical Research and Early Development, Roche Innovation Center Penzberg, Penzberg, Germany.
  • Chen LC; Translational Medicine Oncology, Roche Pharmaceutical Research and Early Development, Roche Innovation Center New York, New York, NY, USA.
  • Dangl M; Discovery Oncology, Roche Pharmaceutical Research and Early Development, Roche Innovation Center Penzberg, Penzberg, Germany.
  • Nichols G; Translational Medicine Oncology, Roche Pharmaceutical Research and Early Development, Roche Innovation Center New York, New York, NY, USA.
  • Pierceall WE; Translational Medicine Oncology, Roche Pharmaceutical Research and Early Development, Roche Innovation Center New York, New York, NY, USA.
Br J Haematol ; 171(3): 432-5, 2015 Nov.
Article em En | MEDLINE | ID: mdl-25855517
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Regulação Leucêmica da Expressão Gênica / Imidazolinas / Proteínas Proto-Oncogênicas c-mdm2 Tipo de estudo: Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Br J Haematol Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Regulação Leucêmica da Expressão Gênica / Imidazolinas / Proteínas Proto-Oncogênicas c-mdm2 Tipo de estudo: Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Br J Haematol Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos