Allospecific CD4(+) T cells retain effector function and are actively regulated by Treg cells in the context of transplantation tolerance.

Chai, Jian-Guo; Ratnasothy, Kulachelvy; Bucy, R Pat; Noelle, Randolph J; Lechler, Robert; Lombardi, Giovanna

Chai, Jian-Guo; Ratnasothy, Kulachelvy; Bucy, R Pat; Noelle, Randolph J; Lechler, Robert; Lombardi, Giovanna.

Afiliação

Chai JG; MRC Centre for Transplantation, King's College London, London, UK.
Ratnasothy K; Therapeutic Immunology Group, Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.
Bucy RP; MRC Centre for Transplantation, King's College London, London, UK.
Noelle RJ; Department of Pathology, University of Alabama, Birmingham, AL, USA.
Lechler R; MRC Centre for Transplantation, King's College London, London, UK.
Lombardi G; Department of Microbiology and Immunology, Dartmouth Medical School, Norris Cotton Cancer Center, Lebanon, NH, USA.

Eur J Immunol ; 45(7): 2017-27, 2015 Jul.

Article em En | MEDLINE | ID: mdl-25944401

Assuntos

Linfócitos T CD4-Positivos/imunologia; Linfócitos T Reguladores/imunologia; Tolerância ao Transplante/imunologia; Transferência Adotiva; Aloenxertos; Animais; Sobrevivência de Enxerto/imunologia; Camundongos; Camundongos Knockout; Camundongos Transgênicos

Palavras-chave

CD4 T cells; CD40L blockade; Tolerance; Transplantation; Treg

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos T CD4-Positivos / Linfócitos T Reguladores / Tolerância ao Transplante Limite: Animals Idioma: En Revista: Eur J Immunol Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Reino Unido

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