Clinical Analysis of Patients with Primary Blepharospasm: A Report of 100 Cases in China.
Eur Neurol
; 73(5-6): 337-41, 2015.
Article
em En
| MEDLINE
| ID: mdl-25997849
ABSTRACT
PURPOSE:
This study explored the clinical characteristics, diagnosis and treatments of primary blepharospasm.METHODS:
In this retrospective analysis, 100 patients with blepharospasm were enrolled. Data were collected from medical records and face-to-face interviews with patients and their families.RESULTS:
The age of onset was 56.4 ± 2.7 (range, 32-76 years). The duration between onset and accurate diagnosis was 38.7 ± 36.0 months (range, 2-120 months). Dry eyes occurred in 54% of the patients. The initial diagnostic accuracy was 10%. Dry eye syndrome, conjunctivitis/keratitis and myasthenia gravis caused the most confusion in the differential diagnosis. Regular botulinum toxin type A injections improved both eyelid spasms and subjective ocular symptoms in all patients.CONCLUSIONS:
Regular botulinum toxin type A injections improved both eyelid spasms and subjective ocular symptoms in blepharospasm patients. The differentiation of primary blepharospasm differentiation from dry eye syndrome, conjunctivitis/keratitis and myasthenia gravis must be improved.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Blefarospasmo
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
/
Qualitative_research
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
País/Região como assunto:
Asia
Idioma:
En
Revista:
Eur Neurol
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
China