The paradoxical role of IL-17 in atherosclerosis.
Cell Immunol
; 297(1): 33-9, 2015 Sep.
Article
em En
| MEDLINE
| ID: mdl-26077826
ABSTRACT
Atherosclerosis is a chronic inflammatory disease mediated by innate and adaptive immune responses. In recent years, CD4(+) T cells (Th1, Th2, Treg, and Th17) have been increasingly studied for their role in atherosclerosis pathophysiology, atheroma stability, plaque rupture, and life-threatening acute coronary syndrome. IL-17, a marker cytokine of Th17 cells, has been reported to be involved in the pathogenesis of rheumatoid arthritis, inflammatory bowel disease, and asthma. However, its role in atherosclerosis has been poorly characterized. This article provides a comprehensive overview of the role of IL-17 in the development of atherosclerosis and human coronary artery diseases.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doença da Artéria Coronariana
/
Interleucina-17
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Aterosclerose
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Células Th17
Limite:
Animals
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Humans
Idioma:
En
Revista:
Cell Immunol
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
China