Epigenetic and molecular signatures of cord blood CD34(+) cells treated with histone deacetylase inhibitors.

Gajzer, D; Ross, J; Winder, L; Navada, S; Zhang, W; Silverman, L; Chaurasia, P

Gajzer, D; Ross, J; Winder, L; Navada, S; Zhang, W; Silverman, L; Chaurasia, P.

Afiliação

Gajzer D; Division of Hematology/Medical Oncology, Department of Medicine, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Ross J; Division of Hematology/Medical Oncology, Department of Medicine, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Winder L; Division of Hematology/Medical Oncology, Department of Medicine, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Navada S; Division of Hematology/Medical Oncology, Department of Medicine, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Zhang W; Department of Medicine Bioinformatics Core, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Silverman L; Division of Hematology/Medical Oncology, Department of Medicine, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Chaurasia P; Division of Hematology/Medical Oncology, Department of Medicine, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Vox Sang ; 110(1): 79-89, 2016 Jan.

Article em En | MEDLINE | ID: mdl-26084882

Assuntos

Antígenos CD34/genética; Cromatina/genética; Epigênese Genética; Células-Tronco Hematopoéticas/efeitos dos fármacos; Inibidores de Histona Desacetilases/farmacologia; Transcriptoma; Antígenos CD34/metabolismo; Células Cultivadas; Cromatina/metabolismo; Sangue Fetal/citologia; Sangue Fetal/metabolismo; Hematopoese/efeitos dos fármacos; Hematopoese/genética; Células-Tronco Hematopoéticas/metabolismo; Humanos; Ácido Valproico/farmacologia

Palavras-chave

cord blood CD34+ cells; epigenetic regulation and gene expression; haematopoietic stem and progenitor cells; histone deacetylase Inhibitors

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Hematopoéticas / Cromatina / Antígenos CD34 / Epigênese Genética / Inibidores de Histona Desacetilases / Transcriptoma Limite: Humans Idioma: En Revista: Vox Sang Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos

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