Synthesis of deuterium-labeled hydroxybupropion.

Li, Jian; Tian, Lei; Zhang, Chi; Chen, Liqin

Li, Jian; Tian, Lei; Zhang, Chi; Chen, Liqin.

Afiliação

Li J; School of Environmental Science, Nanjing Xiaozhuang University, 3601 Hongjing Road, Nanjing, Jiangsu, 211171, China.
Tian L; College of Petroleum Engineering, Yangtze University, 1 Daxue Road, Caidian Zone, Wuhan, Hubei, 434023, China.
Zhang C; Hi-Tech Research Institute and State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing University of Technology, 5 Xinmofan Road, Nanjing, Jiangsu, 210009, China.
Chen L; Hi-Tech Research Institute and State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing University of Technology, 5 Xinmofan Road, Nanjing, Jiangsu, 210009, China.

J Labelled Comp Radiopharm ; 58(10): 411-3, 2015 Aug.

Article em En | MEDLINE | ID: mdl-26216106

ABSTRACT

ABSTRACT

This paper describes the synthesis of deuterium-labeled hydroxybupropion. Mass spectrometry analysis of the compound revealed over 98% deuterium enrichment.

Assuntos

Antidepressivos de Segunda Geração/síntese química; Bupropiona/análogos & derivados; Deutério/química; Bupropiona/síntese química

Palavras-chave

bupropion; deuterium-labeled; hydroxybupropion; metabolite; synthesis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bupropiona / Antidepressivos de Segunda Geração / Deutério Idioma: En Revista: J Labelled Comp Radiopharm Ano de publicação: 2015 Tipo de documento: Article País de afiliação: China

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